2741-30-2

Basic information

• Product Name: 2-[2-[2-(dimethylamino) ethoxy]ethoxy]-ethanol
• Synonyms: 2-[2-[2-(dimethylamino) ethoxy]ethoxy]-ethanol;Dimethyl-2-[2-(2-hydroxyethoxy)ethoxy]ethylamine;N,N-Dimethyl-2-[2-(2-hydroxyethoxy)ethoxy]ethylamine
• CAS NO: 2741-30-2
• Molecular Formula: C₈H₁₉NO₃
• Molecular Weight: 177.24
• Mol File: 2741-30-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 130-134 °C(Press: 12 Torr)
• Appearance: /
• Density: 0.995±0.06 g/cm3(Predicted)
• PKA: 14.36±0.10(Predicted)
• CAS DataBase Reference: 2-[2-[2-(dimethylamino) ethoxy]ethoxy]-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-[2-(dimethylamino) ethoxy]ethoxy]-ethanol(2741-30-2)
• EPA Substance Registry System: 2-[2-[2-(dimethylamino) ethoxy]ethoxy]-ethanol(2741-30-2)

Safety Data

• Hazardous Substances Data: 2741-30-2(Hazardous Substances Data)

Usage

+ State

Liquid

+ Color

Colorless

+ Odor

Faint, sweet

Chemical Class

Glycol ethers

Usage

Solvent in various applications (e.g. paints, coatings, cleaning products)

Synthesis

+ Reaction of dimethylamine with ethylene oxide
+ Reaction of resulting dimethylaminoethanol with ethylene oxide

Toxicity

Low acute toxicity
+ Prolonged exposure to high levels may cause irritation to eyes, skin, and respiratory system

Handling and Safety

Handle with appropriate precautions and follow safety guidelines.

Upstream product

• 75-21-8 oxirane 
• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 124-40-3 dimethyl amine 

Downstream Products

• 1610450-60-6 3-(2-(2-(2-(dimethylamino)ethoxy)ethoxy)ethoxy)-5-methoxyaniline 
• 1610449-86-9 1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-((2-((3-(2-(2-(2-(dimethylamino)ethoxy)ethoxy)ethoxy)-5-methoxyphenyl)amino)pyrimidin-4-yl)oxy)naphthalen-1-yl)urea 
• 1610450-59-3 2-(2-(2-(3-methoxy-5-nitrophenoxy)ethoxy)ethoxy)-N,N-dimethylethanamine 
• 2388-41-2 [2-(2-{2-[Bis-(2,6-dimethyl-phenyl)-methoxy]-ethoxy}-ethoxy)-ethyl]-dimethyl-amine 
• 2212-33-1 {2-[2-(2-Benzhydryloxy-ethoxy)-ethoxy]-ethyl}-dimethyl-amine 

Relevant articles and documents

Coupling of Bioreaction and Separation via Novel Thermosensitive Ionic Liquids Applied in the Baker’s Yeast-Catalyzed Reduction of Ethyl 2-oxo-4-phenylbutyrate

The use of baker’s yeast to reduce ethyl 2-oxo-4-phenylbutyrate (EOPB) in conventional biphasic systems is hindered by low productivities due to mass transfer resistance between the biocatalyst and the substrate partitioned into two different phases. To overcome the limitation, a new reaction-separation coupling process (RSCP) was configured in this study, based on the novel thermosensitive ionic liquids (ILs) with polyoxyethylene-tail. The solubility of ILs in common solvents was investigated to configure the unique thermosensitive ionic liquids–solvent biphasic system (TIBS) in which the reduction was performed. [(CH3)2N(C2H5)(CH2CH2O)2H][PF6] (c2) in 1,2-dimethoxyethane possesses the thermosensitive function of homogeneous at lower temperatures and phase separating at higher temperatures. The phase transformation temperature (PTT) of the mixed system of c2/1,2-dimethoxyethane (v/v, 5:18) was about 33 ?C. The bioreaction takes place in a “homogeneous” liquid phase at 30 ?C. At the end of each reduction run, the system temperature is increased upon to the PTT, while c2 is separated from 1,2-dimethoxyethane with turning the system into two phases. The enantiomeric excesses (e.e.) of ethyl (R)-2-hydroxy-4-phenylbutyrate ((R)-EHPB) increased about 25~30% and the yield of ethyl-2-hydroxy-4-phenylbutyrate (EHPB) increased 35% in TIBS, compared with the reduction in 1,2-dimethoxyethane. It is expected that the TIBS established in this study could provide many future opportunities in the biocatalysis.