274258-29-6

Upstream product

• 126765-23-9 2-[2-(2-chloroethoxy)ethoxy]ethyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 274258-26-3 1-chloro-3,6-dioxa-8-octyl 3-O-p-methoxybenzyl-β-D-galactoside 
• 274258-25-2 2-[2-(2-chloroethoxy)ethoxy]ethyl β-D-galactopyranoside 
• 5197-62-6 2-[2-(chloroethoxy)ethoxy]ethanol 
• 97205-08-8 methyl 2,3,4,6-tetra-O-benzyl-1-thio-β-D-galactopyranoside 
• 274258-28-5 1-chloro-3,6-dioxa-8-octyl 2,4,6-tri-O-acetyl-β-D-galactoside 
• 83-87-4 penta-O-acetyl-α-D-galactopyranose 
• 274258-27-4 1-chloro-3,6-dioxa-8-octyl 2,4,6-tri-O-acetyl-3-p-methoxybenzyl-β-D-galactoside 

Downstream Products

• 725250-84-0 Acetic acid (2R,3S,4S,5R,6R)-5-acetoxy-2-acetoxymethyl-6-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-4-((2R,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester 
• 635302-03-3 1-azido-3,6-dioxa-8-octyl O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranoside 

Relevant academic research and scientific papers

Frontal Affinity Chromatography Coupled to Mass Spectrometry: An Effective Method for Kd Determination and Screening of α-Gal Derivatives Binding to Anti-Gal Antibodies (IgG)

Frontal affinity chromatography with mass spectrometric detection (FAC/MS) was developed as an effective method for rapid determination of Kd values for α-Gal derivatives binding to human anti-Gal IgG antibodies. Using this method, Kd values fo

Conjugates comprising galactose α1,3 galactosyl epitopes and methods of using same

This invention provides conjugates useful for xenotransplantation which comprise a galactose α1,3 galactosyl (αGal) epitope conjugated to a valency platform molecule, preferably a chemically defined valency platform molecule which allows precise valency.

Methods and formulations for reducing circulating antibodies

The invention provides methods for reducing circulating levels of antibodies, particularly disease-associated antibodies. The methods entail administering effective amounts of epitope-presenting carriers to an individual. In other embodiments, ex vivo met