274266-34-1Relevant academic research and scientific papers
4-Quinolones as noncovalent inhibitors of high molecular mass penicillin-binding proteins
Shilabin, Abbas G.,Dzhekieva, Liudmila,Misra, Pushpa,Jayaram,Pratt
supporting information; experimental part, p. 592 - 595 (2012/10/18)
Penicillin-binding proteins (PBPs) are important bacterial enzymes that carry out the final steps of bacterial cell wall assembly. Their DD-transpeptidase activity accomplishes the essential peptide cross-linking step of the cell wall. To date, all attemp
