274677-56-4Relevant academic research and scientific papers
Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex
Legraverend, Michel,Tunnah, Paul,Noble, Martin,Ducrot, Pierre,Ludwig, Odile,Grierson, David S.,Leost, Maryse,Meijer, Laurent,Endicott, Jane
, p. 1282 - 1292 (2007/10/03)
A new series of 2,6,9-trisubstituted purines, characterized by the presence of a common alkynyl substituent at C-2 and a range of different anilino/benzylamino groups at C-6, were synthesized. These compounds were evaluated for their capacity to inhibit c
Synthesis and evaluation of tryprostatin B and demethoxyfumitremorgin C analogues
Wang, Haishan,Usui, Takeo,Osada, Hiroyuki,Ganesan
, p. 1577 - 1585 (2007/10/03)
Tryprostatin B and demethoxyfumitremorgin C are fungal inhibitors of mammalian cell cycle progression at the G2/M transition. N-Alkyl derivatives of the L-Trp-L-Pro diketopiperazine were prepared as analogues of tryprostatin B, and two of these
