27537-87-7 Usage
Uses
Used in Pharmaceutical Industry:
3-amino-6-chloro-2-methyl-4-phenyl-3,4-dihydroquinazolin-4-ol is used as an active pharmaceutical ingredient for its sedative, antidepressive, and antitrichomonas properties. It is particularly effective in treating anxiety, depression, and trichomoniasis, a sexually transmitted parasitic infection.
Additionally, it is recognized as an Alprazolam impurity, which means it can be found as a byproduct during the synthesis of Alprazolam, a widely prescribed medication for anxiety and panic disorders. The presence of 3-amino-6-chloro-2-methyl-4-phenyl-3,4-dihydroquinazolin-4-ol in the manufacturing process may affect the quality and efficacy of the final drug product, making it an important consideration in the pharmaceutical development and quality control processes.
Check Digit Verification of cas no
The CAS Registry Mumber 27537-87-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,3 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27537-87:
(7*2)+(6*7)+(5*5)+(4*3)+(3*7)+(2*8)+(1*7)=137
137 % 10 = 7
So 27537-87-7 is a valid CAS Registry Number.
27537-87-7Relevant academic research and scientific papers
Methods for the production of 4H-s-triazolo[4,3-a][1,4]benzodiazepine 5N-oxides
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, (2008/06/13)
The title compounds are prepared by reacting a 3-amino-3,4-dihydro-4-hydroxy-4-phenylquinazoline with a reactive derivative of a halogenoacetic acid, reacting the resultant halogenoacetyl derivative with a weak acid, reacting the resultant 2-(3-halomethyl-s-triazol-4-yl)benzophenone with hydroxylamine and subjecting the resultant 2-(3-hydroxyamino-methyl-s-triazol-4-yl)benzophenone to dehydration to effect ring closure.
