275375-65-0Relevant academic research and scientific papers
3-SUBSTITUTED-4-ARYLQUINOLIN-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS
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, (2008/06/13)
The present invention provides novel 3-substituted-4-arylquinolin-2-one derivatives having the general formula wherein R, R 1, R 2, R 3, R 4, R 5, R 6 and R 7 are as defined herein, or a non-toxic pharmaceutically acceptable salt thereof which are modulators of the large conductance calcium-activated K + channels and are useful in the treatment of disorders which are responsive to the opening of the potassium channels.
