275377-38-3Relevant academic research and scientific papers
Synthesis of 4,4-difluoroglycosides using ring-closing metathesis
Audouard, Christophe,Fawcett, John,Griffiths, Gerry A.,Percy, Jonathan M.,Pintat, Stephane,Smith, Clive A.
, p. 528 - 541 (2007/10/03)
4-Deoxy-4,4-difluoro-glycosides have been synthesised for the first time via a direct sequence involving ring-closing metathesis and indium-mediated difluoroallylation with 1-bromo-1,1-difluoropropene in water. Two protecting group strategies were explore
Rapid syntheses of difluorinated dihydropyrans
Percy, Jonathan M.,Pintat, Stephane
, p. 607 - 608 (2007/10/03)
A very short reaction sequence opens with metal-mediated addition of commercial bromodifluoropropene to aldehydes; allylation under phase transfer catalysed conditions sets the stage for a ring closing metathesis (RCM) in the presence of commercial Grubbs
