27582-20-3 Usage
Uses
7-Methylimidazo[4,5-b]pyridine does not have any direct applications due to its harmful effects on health. However, it is a subject of research and regulatory efforts in the following areas:
Used in Food Safety and Quality Control:
7-Methylimidazo[4,5-b]pyridine is monitored and regulated in the food industry to ensure the safety and quality of cooked meat and fish products. Its presence is minimized through various methods, such as optimizing cooking conditions and using alternative cooking techniques.
Used in Research and Development:
7-Methylimidazo[4,5-b]pyridine is studied in scientific research to better understand its formation mechanisms, mutagenicity, and carcinogenicity. This knowledge aids in developing strategies to reduce its formation in cooked foods and to establish regulatory guidelines for its presence in food products.
Used in Public Health and Policy Making:
7-Methylimidazo[4,5-b]pyridine is considered in public health initiatives and policy-making to raise awareness about the potential risks associated with its consumption and to promote safer cooking practices and food product regulations.
Check Digit Verification of cas no
The CAS Registry Mumber 27582-20-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,8 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 27582-20:
(7*2)+(6*7)+(5*5)+(4*8)+(3*2)+(2*2)+(1*0)=123
123 % 10 = 3
So 27582-20-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c1-5-2-3-8-7-6(5)9-4-10-7/h2-4,6H,1H3
27582-20-3Relevant academic research and scientific papers
Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses
Wu, Runzhi,Smidansky, Eric D.,Oh, Hyung Suk,Takhampunya, Ratree,Padmanabhan, Radhakrishnan,Cameron, Craig E.,Peterson, Blake R.
, p. 7958 - 7966 (2011/03/19)
Bioisosteric deaza analogues of 6-methyl-9-β-d-ribofuranosylpurine, a hydrophobic analogue of adenosine, were synthesized and evaluated for antiviral activity. Whereas the 1-deaza and 3-deaza analogues were essentially inactive in plaque assays of infectivity, a novel 7-deaza-6-methyl-9-β-d- ribofuranosylpurine analogue, structurally related to the natural product tubercidin, potently inhibited replication of poliovirus (PV) in HeLa cells (IC50 = 11 nM) and dengue virus (DENV) in Vero cells (IC50 = 62 nM). Selectivity against PV over cytotoxic effects to HeLa cells was >100-fold after incubation for 7 h. Mechanistic studies of the 5′-triphosphate of 7-deaza-6-methyl-9-β-d-ribofuranosylpurine revealed that this compound is an efficient substrate of PV RNA-dependent RNA polymerase (RdRP) and is incorporated into RNA mimicking both ATP and GTP.
