27594-72-5Relevant academic research and scientific papers
Anionic hetero[3,3] and [3,5][ rearrangements of hydroxylamine derivatives accompanied with N-O bond cleavage
Endo,Uchida,Hizatate,Shudo
, p. 1096 - 1105 (2007/10/02)
Aromatic and aliphatic N,O-divinylhydroxylamine systems generated in situ from hydroxylamine derivatives smoothly undergo [3,3] rearrangement. The base-catalyzed formation and rearrangement of enolates or dienolates of N-aryl-O-acylhydroxylamines, N,O-dia
α-lactam intermediates in base-promoted reactions of O-sulfonylated hydroxamic acids with nucleophiles
Hoffman, Robert V.,Nayyar, Naresh K.,Chen, Wenting
, p. 5031 - 5034 (2007/10/02)
The reaction of N-(sulfonyloxy) amides with bases proceeds by initial formation of an α-lactam intermediate. A primary kinetic deuterium isotope effect, kH/kD = 2.17, a leaving group effect, β1gCH3 = 0.50, and n
Synthesis of α-Azido and α-Amino Amides from N- Amides
Hoffman, Robert V.,Nayyar, Naresh K.,Chen, Wenting
, p. 2355 - 2359 (2007/10/02)
Effective new syntheses of 2-azido amides and 2-amino amides from N-(mesyloxy) amides 1 have been developed. 2-Azido amides are produced by treating 1 with sodium azide in the presence of 15-crown-5. 2-Amino amides result from the reaction of 1 with vario
