27646-78-2

Basic information

• Product Name: 2-(METHYLAMINO)-1-PROPANOL
• Synonyms: 2-(METHYLAMINO)-1-PROPANOL;2-(methylamino)-1-propanol(SALTDATA: FREE);2-(Methylamino)propan-1-ol;2-(Methylamino)propan-1-ol HCl
• CAS NO: 27646-78-2
• Molecular Formula: C₄H₁₁NO
• Molecular Weight: 89.14
• Mol File: 27646-78-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 148.812°C at 760 mmHg
• Flash Point: 67.439°C
• Appearance: /
• Density: 0.88g/cm³
• Vapor Pressure: 1.595mmHg at 25°C
• Refractive Index: 1.421
• PKA: 14.77±0.10(Predicted)
• CAS DataBase Reference: 2-(METHYLAMINO)-1-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHYLAMINO)-1-PROPANOL(27646-78-2)
• EPA Substance Registry System: 2-(METHYLAMINO)-1-PROPANOL(27646-78-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 27646-78-2(Hazardous Substances Data)

Usage

General Description

2-(Methylamino)-1-propanol is a chemical compound with the molecular formula C4H11NO. It can also be referred to as N-methyl-1-propanolamine. It is a clear, colorless liquid with a fishy odor and is commonly used as a reagent in organic synthesis and as a building block for the production of various pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacturing of surfactants and wetting agents. Additionally, it has applications in the production of herbicides, pesticides, and dyes. 2-(METHYLAMINO)-1-PROPANOL is considered to be relatively stable under normal conditions but should be handled with caution due to its potential to cause skin and eye irritation upon contact.

InChI:InChI=1/C4H11NO/c1-4(3-6)5-2/h4-6H,3H2,1-2H3

Upstream product

• 600-21-5 N-methylalanine 
• 35023-55-3 N-methyl-L-alanine methyl ester 
• 5893-10-7 (S)-2-formamidopropanoic acid 
• 32221-83-3 (S)-N-formylalanine methyl ester 
• 3913-67-5 N-methylalanine 
• 34101-08-1 N-ethylthiothioxomethyl-L-alanine 
• 56428-90-1 ethyl-α-methylaminopropionate 
• 170749-86-7 2-(N-benzyl-N-methylamino)propan-1-ol 

Downstream Products

• 573701-30-1 (2S)-2-[benzyl(methyl)amino]propan-1-ol 
• 95421-91-3 (S)-AlaNOP 

Relevant articles and documents

4,5,6,7-TETRAHYDRO-1 H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS

The present invention relates to compounds of formula (I) or formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R1-R3 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.

NO-RELEASING NONOATE(OXYGEN-BOUND)CHROMENE CONJUGATES

The present invention provides NO-releasing NONOate(oxygen bound)chromene conjugates, having the structure of Formula (I): wherein Z, R1, R2, R3, R4, R5, R6, and R7 are as defined in the detailed description; pharmaceutical compositions comprising at least one compound of Formula (I); and methods useful for healing wounds, preventing and treating cancer, or treating actinic keratosis, cystic fibrosis, or acne, using a compound of Formula (I).

COMPOUNDS

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.