276680-16-1

Basic information

• Product Name: 5-furan-2-yl-3,7-bis-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one
• CAS NO: 276680-16-1
• Molecular Weight: 457.51
• Mol File: 276680-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-furan-2-yl-3,7-bis-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-furan-2-yl-3,7-bis-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one(276680-16-1)
• EPA Substance Registry System: 5-furan-2-yl-3,7-bis-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one(276680-16-1)

Safety Data

• Hazardous Substances Data: 276680-16-1(Hazardous Substances Data)

Upstream product

• 77607-69-3 2-Amino-4-furan-2-yl-6-(4-methoxy-phenyl)-nicotinonitrile 
• 114570-69-3 3-(2-furyl)-1-(4-methoxyphenyl)propen-1-one 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 276680-11-6 2-Amino-4-furan-2-yl-6-(4-methoxy-phenyl)-nicotinamide 

Relevant articles and documents

Synthesis of some 5-furfuryl pyrido[2,3-d] pyrimidines and 1-ethyl-5-furfuryl pyrido[2,3-d] pyrimidines as possible antitumor & anticancer agents

Synthesis of some novel 5-furfuryl pyrido[2,3-d]pyrimidines was carried out by the condensation of 2-amino-3-cyano-4-furfuryl-6-substituted pyridine with various arylisothiocyanates, thiourea and carbondisulphide. These compounds on treatment with ethylbromide using phase transfer catalyst gave 1-ethyl-5-furfuryl pyrido[2,3-d]pyrimidines. The structure of the compounds has been established by elemental, IR and NMR studies. The compounds thus synthesized were screened for their antimicrobial activity.