276680-25-2Relevant academic research and scientific papers
Synthesis of some 5-furfuryl pyrido[2,3-d] pyrimidines and 1-ethyl-5-furfuryl pyrido[2,3-d] pyrimidines as possible antitumor & anticancer agents
Singh, Gajendra,Sharma, Anoop K.,Mishra,Prakash
, p. 83 - 93 (2007/10/03)
Synthesis of some novel 5-furfuryl pyrido[2,3-d]pyrimidines was carried out by the condensation of 2-amino-3-cyano-4-furfuryl-6-substituted pyridine with various arylisothiocyanates, thiourea and carbondisulphide. These compounds on treatment with ethylbromide using phase transfer catalyst gave 1-ethyl-5-furfuryl pyrido[2,3-d]pyrimidines. The structure of the compounds has been established by elemental, IR and NMR studies. The compounds thus synthesized were screened for their antimicrobial activity.
