276702-52-4

Basic information

• Product Name: 2,6-dichloro-3-nitrobenzene-1-sulfonic acid
• Synonyms: 2,6-dichloro-3-nitrobenzene-1-sulfonic acid;2,6-Dichloro-3-nitrobenzenesulfonic acid
• CAS NO: 276702-52-4
• Molecular Formula: C₆H₃Cl₂NO₅S
• Molecular Weight: 272.06272
• Mol File: 276702-52-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,6-dichloro-3-nitrobenzene-1-sulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dichloro-3-nitrobenzene-1-sulfonic acid(276702-52-4)
• EPA Substance Registry System: 2,6-dichloro-3-nitrobenzene-1-sulfonic acid(276702-52-4)

Safety Data

• Hazardous Substances Data: 276702-52-4(Hazardous Substances Data)

Usage

General Description

2,6-dichloro-3-nitrobenzene-1-sulfonic acid is a chemical compound with the molecular formula C6H3Cl2NO5S. It is a sulfonic acid derivative of nitrobenzene, with two chlorine atoms at the 2 and 6 positions and a nitro group at the 3 position of the benzene ring. 2,6-dichloro-3-nitrobenzene-1-sulfonic acid is commonly used as an intermediate in the synthesis of various dyes, pigments, and pharmaceuticals. It has the potential to be a skin and eye irritant and should be handled with caution. Additionally,

Upstream product

• 6579-54-0 2,6-dichlorobenzenesulfonyl chloride 
• 6697-96-7 o-dichlorobenzenesulfonic acid 

Downstream Products

• 444045-60-7 3-[3-([1,4']Bipiperidinyl-1'-sulfonyl)-4-chloro-2-hydroxy-phenylamino]-4-chloro-cyclobut-3-ene-1,2-dione 
• 444045-54-9 3-Chloro-4-[4-chloro-2-hydroxy-3-(4-methyl-[1,4]diazepane-1-sulfonyl)phenylamino]-cyclobut-3-ene-1,2-dione 
• 934275-49-7 2-([1,4']bipiperidinyl-1'-sulfonyl)-3-chloro-6-nitro-phenol 
• 934275-57-7 1'-(2,6-dichloro-3-nitro-benzenesulfonyl)-[1,4']bipiperidinyl 
• 444045-59-4 6-Amino-2-([1,4']bipiperidinyl-1'-sulfonyl)-3-chloro-phenol 
• 934275-47-5 3-chloro-2-(4-ethyl-piperazine-1-sulfonyl)-6-nitro-phenol 
• 934275-56-6 1-(2,6-dichloro-3-nitro-benzenesulfonyl)-4-methyl-[1,4]diazepane 
• 934275-48-6 3-chloro-2-(4-methyl-[1,4]diazepane-1-sulfonyl)-6-nitro-phenol 
• 934275-55-5 1-(2,6-dichloro-3-nitro-benzenesulfonyl)-4-ethyl-piperazine 
• 444045-53-8 6-Amino-3-chloro-2-(4-methyl-[1,4]diazepane-1-sulfonyl)-phenol 
• 934275-42-0 6-amino-3-chloro-2-[(4-ethyl-1-piperazinyl)sulfonyl]phenol 
• 276702-35-3 2,6-dichloro-N-(2-methoxy-ethyl)-3-nitro-benzenesulfonamide 
• 276702-37-5 6-chloro-2-hydroxy-N-(2-methoxy-ethyl)-3-nitro-benzenesulfonamide 
• 276702-39-7 N-(2-methoxyethyl)-3-amino-6-chloro-2-hydroxybenzenesulfonamide 

Relevant articles and documents

Comparison of N,N′-diarylsquaramides and N,N′-diarylureas as antagonists of the CXCR2 chemokine receptor

N,N′-diarylsquaramides were prepared and evaluated as antagonists of CXCR2. The compounds were found to be potent and selective antagonists of CXCR2. Significant differences in SAR was observed relative to the previously described N,N′-diarylurea series. As was the case in the N,N′-diarylurea series, placing sulfonamide substituent adjacent to the acidic phenol significantly reduced the clearance in rat pharmacokinetic studies.

Il-8 receptor antagonists

This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).