276702-70-6Relevant academic research and scientific papers
Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders
Xu, Heng,Lu, Hongfu,Xu, Zhongmiao,Luan, Linbo,Li, Chengyong,Xu, Yan,Dong, Kelly,Zhang, Jinqiang,Li, Xiong,Li, Yvonne,Liu, Gentao,Gong, Sophie,Zhao, Yong-Gang,Liu, Ailian,Zhang, Yueting,Zhang, Wei,Cai, Xin,Xiang, Jia-Ning,Elliott, John D.,Lin, Xichen
supporting information, p. 397 - 402 (2016/05/19)
Structure-activity relationship exploration of the historical biarylurea series led to the identification of novel CNS penetrant CXCR2 antagonists with nanomolar potency, favorable PK profile, and good developability potentials. More importantly, the key
METHOD OF TREATMENT
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Page/Page column 17, (2009/04/25)
This invention relates to the use of a sulfonamide substituted diphenyl urea compound to treat cystic fibrosis, or the symptoms associated with cystic fibrosis.
METHOD OF TREATMENT
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Page/Page column 10, (2008/06/13)
This invention relates to the use of sulfonamide substituted diphenyl urea compounds to treat endometriosis.
IL-8 RECEPTOR ANTAGONISTS
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Page/Page column 13, (2010/11/08)
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Il-8 receptor antagonists
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, (2008/06/13)
This invention relates to the novel use of sulfonamide squaramides in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
IL-8 RECEPTOR ANTAGONISTS
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Page 13-14, (2008/06/13)
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
Hydroxy diphenyl urea sulfonamides as IL-8 receptor antagonists
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, (2008/06/13)
Novell IL-8 compounds and methods of using them are provided.
