688763-67-9

Basic information

• Product Name: 4-(6-chloro-3-[3-(2-chloro-3-fluorophenyl)-ureido]-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester
• Synonyms: 4-(6-chloro-3-[3-(2-chloro-3-fluorophenyl)-ureido]-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 688763-67-9
• Molecular Weight: 563.434
• Mol File: 688763-67-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(6-chloro-3-[3-(2-chloro-3-fluorophenyl)-ureido]-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-chloro-3-[3-(2-chloro-3-fluorophenyl)-ureido]-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester(688763-67-9)
• EPA Substance Registry System: 4-(6-chloro-3-[3-(2-chloro-3-fluorophenyl)-ureido]-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester(688763-67-9)

Safety Data

• Hazardous Substances Data: 688763-67-9(Hazardous Substances Data)

Upstream product

• 102940-86-3 3-chloro-3-fluorobenzoic acid 
• 21900-57-2 2-chloro-3-fluorobenzoic acid chloride 
• 455-38-9 3-fluorobenzoic acid 
• 960495-44-7 2-(tert-butyl)-6-chloro-7-(piperazin-1-ylsulfonyl)benzo[d]oxazole 
• 276702-70-6 4-(3-Amino-6-chloro-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 934685-42-4 2-chloro-3-fluoro-benzoyl azide 
• 93110-05-5 2-chloro-1-fluoro-3-isocyanatobenzene 

Downstream Products

• 276702-70-6 4-(3-Amino-6-chloro-2-hydroxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 960495-43-6 Elubrixin tosylate 
• 688763-65-7 Elubrixin hydrochloride 

Relevant articles and documents

METHOD OF TREATMENT

This invention relates to the use of a sulfonamide substituted diphenyl urea compound to treat cystic fibrosis, or the symptoms associated with cystic fibrosis.

IL-8 RECEPTOR ANTAGONISTS

This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).