276868-00-9Relevant articles and documents
The synthesis and vasopressin (AVP) antagonist activity of a novel series of N-Aroyl-2,4,5,6-tetrahydropyrazolo-[3,4-d]thieno[3,2-b]azepines
Albright, J. Donald,Santos, Efren G. Delos,Dusza, John P.,Chan, Peter S.,Coupet, Joseph,Ru, Xun,Mazandarani
, p. 695 - 698 (2007/10/03)
Synthesis and SAR of N-[4-[(4,5-dihydropyrazolo[3,4-d]thieno[3,2-b]azepin-6(2H)-yl)carbonyl]phenyl]be nzamides as arginine vasopressin (AVP) receptor antagonists are discussed. Potent orally active AVP receptor antagonists are produced when the benzamide moiety contains a phenyl group at the 2-position. Similar analogues of 4,6,7,8-tetrahydro-5H-thieno[3,2-b]azepine and VPA-985 are reported. (C) 2000 Elsevier Science Ltd. All rights reserved.
TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS
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, (2008/06/13)
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