276879-27-7

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 247587-57-1 (4R,5S)-4-tert-butyldimethylsilyloxymethyl-5-tert-butyldimethylsilyloxycyclohex-2-en-1-one 
• 276879-09-5 (2S,3S)-3-Vinyl-butane-1,2,4-triol 
• 276879-10-8 tert-Butyl-dimethyl-((S)-(S)-2-oxiranyl-but-3-enyloxy)-silane 
• 192863-92-6 (2S,3S)-1-Benzyloxy-3-benzyloxymethyl-pent-4-en-2-ol 
• 276879-11-9 3-(tert-butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-hex-5-enoic acid methyl ester 
• 276879-12-0 3-(tert-butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-methyl-cyclohexanone 

Relevant academic research and scientific papers

Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert- butyldimethylsiloxy)-2-cyclohexenone as a useful chiral building block for preparation of substituted cyclohexane rings: Synthesis and its highly stereoselective reaction with RCu(CN)Li

Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert- butyldimethylsiloxy)-2-cyclohexenone (2) has been synthesized in 25% overall yield starting from easily available 1,4-bis(benzyloxy)-2,3-epoxy butane (3). The enone 2 reacts with excellent stereoselectivity with RCu(CN)Li thus working as an efficient chiral building block for preparation of substituted cyclohexane compounds. (C) 2000 Elsevier Science Ltd.