192863-92-6

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 80183-15-9 (2R,3R)-1,4-bis(benzyloxy)-2,3-epoxy butane 

Downstream Products

• 276879-12-0 3-(tert-butyl-dimethyl-silanyloxy)-4-(tert-butyl-dimethyl-silanyloxymethyl)-5-methyl-cyclohexanone 
• 276879-27-7 (4S,5R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-methyl-cyclohex-2-enone 
• 247587-57-1 (4R,5S)-4-tert-butyldimethylsilyloxymethyl-5-tert-butyldimethylsilyloxycyclohex-2-en-1-one 

Relevant academic research and scientific papers

Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert- butyldimethylsiloxy)-2-cyclohexenone as a useful chiral building block for preparation of substituted cyclohexane rings: Synthesis and its highly stereoselective reaction with RCu(CN)Li

Optically active trans-4-(tert-butyldimethylsiloxymethyl)-5-(tert- butyldimethylsiloxy)-2-cyclohexenone (2) has been synthesized in 25% overall yield starting from easily available 1,4-bis(benzyloxy)-2,3-epoxy butane (3). The enone 2 reacts with excellent stereoselectivity with RCu(CN)Li thus working as an efficient chiral building block for preparation of substituted cyclohexane compounds. (C) 2000 Elsevier Science Ltd.