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276888-52-9

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276888-52-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 276888-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,6,8,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 276888-52:
(8*2)+(7*7)+(6*6)+(5*8)+(4*8)+(3*8)+(2*5)+(1*2)=209
209 % 10 = 9
So 276888-52-9 is a valid CAS Registry Number.

276888-52-9Relevant articles and documents

COMPOUNDS AND COMPOSITIONS AS CHANNEL ACTIVATING PROTEASE INHIBITORS

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Page/Page column 34-35, (2008/12/08)

The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.

New synthetic technology for efficient construction of α-hydroxy-β-amino amides via the passerini reaction

Semple, J. Edward,Owens, Timothy D.,Nguyen, Khanh,Levy, Odile E.

, p. 2769 - 2772 (2007/10/03)

The Passerini reaction of N-protected amino aldehydes, isonitriles, and TFA using pyridine-type bases proceeds under mild conditions and directly affords α-hydroxy-β-amino amide derivatives in moderate to high yields. These adducts are readily hydrolyzed to αhydroxy-β-amino carboxylic acids. Application of these key intermediates to concise syntheses of P1-α-ketoamide protease inhibitors is illustrated.

MORPHOLINE CONTAINING AMINO ACID DERIVATIVES

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, (2008/06/13)

Amino acid derivatives represented by formula STR1 wherein His represents an L-histidyl group, X represents a straight or branched alkoxy group having 1 to 7 carbon atoms, a straight or branched alkylamino group having 1 to 7 carbon atoms, a cycloalkyloxy

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