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Usage

Uses

Used in Synthetic Chemistry:
PropanaMide, 2-Methyl-N-ethylis used as a chemical intermediate for the synthesis of various compounds. Its role in synthetic chemistry is crucial for the development of new materials and pharmaceuticals.
Used in Pharmaceutical Research:
As a derivative of Isobutyryl chloride, PropanaMide, 2-Methyl-N-ethylmay have potential applications in the pharmaceutical industry. It can be used as a building block for the development of new drugs, targeting specific medical conditions.
Used in Chemical Research:
PropanaMide, 2-Methyl-N-ethylis also used in chemical research to study its properties and potential reactions with other compounds. This research can lead to the discovery of new chemical processes and applications.

Upstream product

• 75-04-7 ethylamine 
• 79-30-1 isobutyryl chloride 
• 88876-29-3 2-bromo-N-ethylisobutyramide 

Relevant academic research and scientific papers

Radical reaction by a combination of phosphinic acid and a base in aqueous media

Treatment of various organic halides with phosphinic acid (hypophosphorous acid) in aqueous ethanol in the presence of a radical initiator and a base gave the corresponding reduced products in high yields. Addition of a base is indispensable for the reduction of halides by phosphinic acid. Allylic ether of o-iodophenol or 2-haloalkanal allylic acetal underwent radical cyclization under the same conditions to afford the corresponding cyclic product in excellent yield. Deuterated phosphinic acid was found to be an efficient chain carrier for the radical deuteration of organic halides. For example, a deuterium oxide solution of deuterated phosphinic acid, potassium carbonate, 2,2′-azobis(isobutyramidine) dihydrochloride as an initiator, and p-iodobenzoic acid was heated at reflux to give p-deuteriobenzoic acid in 94% yield. A mixed dioxane/D2O solvent system combined with DBU and potassium peroxodisulfate was crucial to deuterate hydrophobic substrates in high yields and with high deuterium incorporation. Complete deuterium incorporation was accomplished only by the reaction in D2O without an organic cosolvent and an organic base.