27749-01-5Relevant academic research and scientific papers
The benzyne Fischer-indole reaction
McAusland, Donald,Seo, Sangwon,Pintori, Didier G.,Finlayson, Jonathan,Greaney, Michael F.
, p. 3667 - 3669 (2011/09/16)
A new approach to the Fischer-indole synthesis is reported that uses the reactive intermediate benzyne. The addition of N-tosyl hydrazones to arynes, generated through fluoride activation of 2-(trimethylsilyl)phenyl triflate precursors, leads to efficient
