27752-28-9

Upstream product

• 27752-24-5 6-methoxy-2-methyl-3,4-dihydronaphthalen-1(2H)-one 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 29784-46-1 2-Methyl-2-(β-chlorallyl)-6-methoxy-tetralon-(1) 
• 17850-66-7 2-(β-Chlorallyl)-6-methoxy-tetralon-(1) 
• 27752-25-6 3,4-Dihydro-6-methoxy-2-methyl-2-(2-propynyl)-1(2H)naphthalenon 
• 27752-26-7 2-Acetonyl-2-methyl-1,2,3,4-tetrahydro-6-methoxy-1-oxo-naphthalin 
• 153683-09-1 (3S,6R,7aR)-6-[2-(2-Bromo-5-methoxy-phenyl)-ethyl]-3-isopropyl-6,7a-dimethyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one 
• 153683-14-8 2-(2-Bromo-5-methoxyphenyl)-1-iodoethane 
• 75534-35-9 2-(2-bromo-5-methoxyphenyl)ethan-1-ol 
• 1798-09-0 m-methoxyphenylacetic acid 
• 5020-41-7 2-(3-methoxyphenyl)-ethanol 
• 27752-26-7 (R)-6-Methoxy-2-methyl-2-(2-oxo-propyl)-3,4-dihydro-2H-naphthalen-1-one 

Relevant academic research and scientific papers

Synthesis of Enantiomerically Pure Hydrinden-2-ones and Benzinden-2-ones via Asymmetric Alkylations of Chiral Bicyclic Lactams

A route to the titled compounds in >99percent ee was achieved from sequential diastereoselective alkylations of chiral, nonracemic bicyclic lactams 6 and 15.An intramolecular addition of the organolithium species derived from 17a-c and 28a-d gave, after hydrolysis, diketones 25a-c and 30a-d, which were cyclized to the titled compounds 4a-c and 31a-d.As an example of the versatility of this method, the ABC ring system of the triterpene stelliferin A, isolated from marine organisms, was prepared in high enantiomeric excess.