27758-67-4Relevant academic research and scientific papers
TERPENOIDS. SYNTHESIS OF (PLUS OR MINUS)-U- CADINENE
VIG OP,CHUGH OP,MATTA KL
, p. 29 - 32 (2007/10/07)
The starting compound 2-isopropyl- 4- carbethoxybutanal when subjected to Wittig reaction with methallylidenetriphenylphosphorane affords 2-methyl- 5- isopropyl - 7 - carbethoxy- 1,3 - heptadiene. The resulting product on Diels-Alder reaction with ethyl acrylate yields 1-methyl- 4- carbethoxy - 3 - (1 - isopropyl - 3 - carbethoxy -n - propyl) - cyclohex- lene. Cyclization of the diester followed by hydrolysis and decarboxylation gives 2-methyl- 5-oxo- 8- isopropyl - delta- l - decalene which on Wittig reaction with methylenetriphenylphosphorane furnishes (plus or minus)-U- cadinene.
