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Usage

Uses

Used in Pharmaceutical Industry:
4-chloro-3-oxobutyric acid is used as a key intermediate for the synthesis of various pharmaceuticals. It plays a crucial role in the production of drugs that target a wide range of medical conditions, including pain relief, inflammation, and infectious diseases.
Used in Agrochemical Industry:
4-chloro-3-oxobutyric acid is used as a building block for the synthesis of agrochemicals, such as insecticides, herbicides, and fungicides. Its reactivity and properties make it an essential component in the development of effective and environmentally friendly agricultural products.
Used in Chemical Intermediates Production:
4-chloro-3-oxobutyric acid is used as a versatile chemical intermediate in the production of various organic compounds. Its unique structure and reactivity enable the synthesis of complex molecules that are used in a wide range of industries, including plastics, coatings, and textiles.
Used in Organic Chemistry Research:
4-chloro-3-oxobutyric acid is used as a valuable reagent in organic chemistry research. Its properties and reactivity make it an essential tool for the development of new synthetic methods, the study of reaction mechanisms, and the exploration of novel chemical transformations.

InChI:InChI=1/C4H5ClO3/c5-2-3(6)1-4(7)8/h1-2H2,(H,7,8)

Upstream product

• 36038-30-9 Trichlor-penten-⁽¹⁾-in-⁽³⁾-saeure-⁽⁵⁾ 
• 18457-04-0 bis(trimethylsilyl) malonate 
• 79-04-9 chloroacetyl chloride 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 41295-64-1 4-chloroacetoacetyl chloride 

Downstream Products

• 41295-55-0 4-(chloromethyl)-7-methoxy-2H-chromen-2-one 
• 14337-41-8 1-chloro-3-(hydroxyimino)acetone 
• 1533453-13-2 1-chloro-4-cyclohexylhex-5-en-2-one 
• 1533453-29-0 4-benzyl-1-chloro-4-methylhex-5-en-2-one 
• 1234174-15-2 C₁₀H₁₁ClN₂O 
• 1029521-10-5 2-benzyl-5-chloromethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol 
• 1028843-08-4 methyl 4-((2,3-difluorophenyl)thio)-3-oxobutanoate 

Relevant academic research and scientific papers

OXADIAZOLE COMPOUNDS

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.

PROCESS FOR PREPARING DIHYDROISOXAZOLE DERIVATIVES

The present invention relates to a novel process for preparing dihydroisoxazole derivatives.

3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid

Heterocyclyl derivatives of oxy-imino-substituted cephalosporins are disclosed, such, for instance the compound 3-[(8-amino-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid and its pharmaceutically and veterinarily acceptable salts. The compounds of the application have high antibacterial activity against Gram-positive and Gram-negative bacteria, including strong beta-lactamase producer Gram-negative microorganisms.

3-Hydroxy-3,4-dicarbamoylbutyric acid and salts

It is disclosed that citric acid or its salts are obtained by the hydrolysis of a 3-carbamoyl-3-hydroxy-4-cyanobutyric acid or salt, that a 3-carbamoyl-3-hydroxy-4-cyanobutyric acid or salt is obtained from a 3-carbamoyl-3,4-epoxybutyric acid or salt, that a 3-carbamoyl-3,4-epoxybutyric acid or salt is obtained from a 3-carbamoyl-3-hydroxy-4-halobutyric acid or salt, that a 3-carbamoyl-3-hydroxy-4-halobutyric acid is obtained from a 3-cyano-3-hydroxy-4-halobutyric acid or salt, that a 3-cyano-3-hydroxy-4-halobutyric acid or salt is obtained from a 3-oxo-4-halobutyric acid or salt, that a 3-oxo-4-halobutyric acid or salt is obtained from a 3-oxo-4-halobutyryl halide, and that a 3-oxo-4-halobutyryl halide is obtained from diketene. Preferred halide compounds are compounds of chlorine.

Method for the production of haloacetoacetic acids

Haloacetoacetic acids of the formula wherein R1 represents chlorine or bromine and R2 and R3 each represents hydrogen, chlorine or bromine, are obtained by converting diketene into a chloro or bromo acetoacetic acid halide by means of chlorine or bromine at a temperature of from about -10° to -40°C, and the acetoacetic chloro or bromoacetoacetic acid halide is converted into the corresponding acid by hydrolysis with a stoichiometrically equivalent (or excess) quantity of water.