27807-84-7

Basic information

• Product Name: 4-chloro-3-oxobutyric acid
• Synonyms: 4-chloro-3-oxobutyric acid;4-Chloroacetoacetic acid;4-Chloro-3-oxobutanoic acid
• CAS NO: 27807-84-7
• Molecular Formula: C₄H₅ClO₃
• Molecular Weight: 136.5337
• EINECS: 248-665-8
• Mol File: 27807-84-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 67-69 °C
• Boiling Point: 284.8°Cat760mmHg
• Flash Point: 126.1°C
• Appearance: /
• Density: 1.397g/cm³
• Vapor Pressure: 0.000752mmHg at 25°C
• Refractive Index: 1.465
• PKA: 2.44±0.32(Predicted)
• CAS DataBase Reference: 4-chloro-3-oxobutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-3-oxobutyric acid(27807-84-7)
• EPA Substance Registry System: 4-chloro-3-oxobutyric acid(27807-84-7)

Safety Data

• Hazardous Substances Data: 27807-84-7(Hazardous Substances Data)

Usage

General Description

4-chloro-3-oxobutyric acid is a chemical compound with the molecular formula C4H5ClO3. It is an organic compound containing a chlorine atom and a ketone group. This chemical is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of various chemical intermediates. It is also used as a building block for the synthesis of complex molecules and is an essential reagent in organic chemistry. Its properties and reactivity make it a valuable compound for a wide range of chemical processes and applications.

InChI:InChI=1/C4H5ClO3/c5-2-3(6)1-4(7)8/h1-2H2,(H,7,8)

Upstream product

• 18457-04-0 bis(trimethylsilyl) malonate 
• 79-04-9 chloroacetyl chloride 
• 638-07-3 ethyl (2-chloroaceto)acetate 
• 41295-64-1 4-chloroacetoacetyl chloride 
• 36038-30-9 Trichlor-penten-⁽¹⁾-in-⁽³⁾-saeure-⁽⁵⁾ 

Downstream Products

• 41295-55-0 4-(chloromethyl)-7-methoxy-2H-chromen-2-one 
• 14337-41-8 1-chloro-3-(hydroxyimino)acetone 
• 1533453-13-2 1-chloro-4-cyclohexylhex-5-en-2-one 
• 1533453-29-0 4-benzyl-1-chloro-4-methylhex-5-en-2-one 
• 1234174-15-2 C₁₀H₁₁ClN₂O 
• 1029521-10-5 2-benzyl-5-chloromethyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol 
• 1028843-08-4 methyl 4-((2,3-difluorophenyl)thio)-3-oxobutanoate 

Relevant articles and documents

OXADIAZOLE COMPOUNDS

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for treating cancers. Specific cancers include those that are mediated by YAP/TAZ or those that are modulated by the interaction between YAP/TAZ and TEAD.

An improved procedure for the preparation of 1-aryl-4-hydroxy-1H-pyrazoles

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3-Hydroxy-3,4-dicarbamoylbutyric acid and salts

It is disclosed that citric acid or its salts are obtained by the hydrolysis of a 3-carbamoyl-3-hydroxy-4-cyanobutyric acid or salt, that a 3-carbamoyl-3-hydroxy-4-cyanobutyric acid or salt is obtained from a 3-carbamoyl-3,4-epoxybutyric acid or salt, that a 3-carbamoyl-3,4-epoxybutyric acid or salt is obtained from a 3-carbamoyl-3-hydroxy-4-halobutyric acid or salt, that a 3-carbamoyl-3-hydroxy-4-halobutyric acid is obtained from a 3-cyano-3-hydroxy-4-halobutyric acid or salt, that a 3-cyano-3-hydroxy-4-halobutyric acid or salt is obtained from a 3-oxo-4-halobutyric acid or salt, that a 3-oxo-4-halobutyric acid or salt is obtained from a 3-oxo-4-halobutyryl halide, and that a 3-oxo-4-halobutyryl halide is obtained from diketene. Preferred halide compounds are compounds of chlorine.