27816-23-5

Usage

Uses

Used in Medical Applications:
2-Methoxyethyl 2-cyanoacrylate is used as a surgical adhesive for its rapid curing time and excellent bonding strength, facilitating efficient wound closure and tissue adhesion in medical procedures.
Used in Dental Applications:
In dentistry, 2-Methoxyethyl 2-cyanoacrylate serves as a dental restorative material, providing strong bonds to dental tissues and offering a durable solution for various dental repairs and restorations.
Used in Industrial Applications:
2-Methoxyethyl 2-cyanoacrylate is utilized as an industrial adhesive for its ability to bond a wide range of materials, including plastics, rubber, metal, and ceramics, making it a popular choice for manufacturing processes and product assembly.
Used in General Adhesive and Sealant Formulations:
2-methoxyethyl 2-cyanoacrylate is employed as a key ingredient in adhesive and sealant formulations across various industries, leveraging its fast-acting and strong bonding properties for efficient and reliable joining of different surfaces.
It is important to handle 2-methoxyethyl 2-cyanoacrylate with care due to its potential to cause skin and eye irritation, ensuring proper safety measures are in place during its use.

InChI:InChI=1/C7H9NO3/c1-6(5-8)7(9)11-4-3-10-2/h1,3-4H2,2H3

Synthetic route

Dimethoxymethane (109-87-5) + 2-methoxyethyl cyanoacetate (10258-54-5) → 2-methoxyethyl 2-cyanoacrylate (27816-23-5)

Conditions	Yield
With piperdinium acetate at 130℃; for 6h;	52%

formaldehyd (50-00-0) + 2-methoxyethyl cyanoacetate (10258-54-5) → 2-methoxyethyl 2-cyanoacrylate (27816-23-5)

Conditions	Yield
With methanol; sodium methylate Erhitzen des Reaktionsprodukts mit Phosphor(V)-oxid, Schwefeldioxid und Hydrochinon unter vermindertem Druck auf 160-220gradC;
(i) piperidine, aq. NaOH, (ii) SO2, P2O5, benzene-1,4-diol, (heating); Multistep reaction;

Upstream product

• 50-00-0 formaldehyd 
• 10258-54-5 2-methoxyethyl cyanoacetate 
• 109-87-5 Dimethoxymethane 

Relevant academic research and scientific papers

Method for synthesizing cyanoacrylate

The invention discloses a method for synthesizing cyanoacrylate. The method comprises steps as follows: cyanoacetic ester and dialkoxymethane are taken as raw materials and have a condensation reaction under the catalytic action of a catalyst, and a reaction mixture of a cyanoacrylate containing oligomer and byproduct alcohol is obtained; the byproduct alcohol and unreacted dialkoxymethane are separated, a stabilizer is added to the remaining reaction mixture, cracking distillation under the reduced pressure is performed, and a cyanoacrylate crude product is obtained; the crude product is purified, and a finished product, namely, cyanoacrylate is obtained. Solid paraformaldehyde is not used any more, the difficulty of solid feeding is reduced, a dehydration step is not required, a dehydrating agent is not required to be used, defects of a condensation polymerization process using solid paraformaldehyde and using a solvent for continuous dehydration in conventional cyanoacrylate synthesis are avoided, the reaction process is easier to control, the process is simple, the operability is high, the method is economical and reasonable, discharge of three wastes and pollution to the environment are greatly reduced, and the method has good social benefits.

Process for preparing 1,1-disubstituted ethylenic monomers

The present invention relates to a process for preparing 1,1-disubstituted ethylene monomers having general formula (I) from a compound of general formula (II) and an active methylene compound of general formula (III) using a catalytic amount of an ammonium or iminium salt in homogeneous phase or supported on a solid substrate. Said process allows the direct synthesis of the monomers and finds application in the preparation of a wide variety of monomers. The products obtained are reactive monomers of high purity which find application in the field of fast curing adhesives.