278169-72-5

Basic information

• Product Name: (R)-phenyl-1,2-bis(methanesulfonyloxy)ethane
• Synonyms: (R)-phenyl-1,2-bis(methanesulfonyloxy)ethane
• CAS NO: 278169-72-5
• Molecular Weight: 294.35
• Mol File: 278169-72-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-phenyl-1,2-bis(methanesulfonyloxy)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-phenyl-1,2-bis(methanesulfonyloxy)ethane(278169-72-5)
• EPA Substance Registry System: (R)-phenyl-1,2-bis(methanesulfonyloxy)ethane(278169-72-5)

Safety Data

• Hazardous Substances Data: 278169-72-5(Hazardous Substances Data)

Upstream product

• 16355-00-3 (R)-1-phenyl-1,2-ethanediol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 278169-73-6 (R)-1-phenyl-spiro[2.4]hepta-4,6-diene 
• 72397-56-9 (2R)-dimethyl 2-phenylcyclopropane-1,1-dicarboxylate 

Relevant articles and documents

A new roate to cationic half-sandwich ruthenium(II) complexes with chiral cyclopentadienylphosphane ligands

Optically active cyclopentadieny-linked phosphane ligands Ln of general formula C5H5CH2CH(R) PR′2 (R = Ph, R′ = Ph, L1; R = Ph, R′ = Cy, L2; R = mesityl, R′ = Ph, L3)

Stereospecific copper(II)-catalyzed tandem ring opening/oxidative alkylation of donor-acceptor cyclopropanes with hydrazones: Synthesis of tetrahydropyridazines

Aerobic copper(II)-catalyzed tandem ring opening and oxidative C-H alkylation of donor-acceptor cyclopropanes with bisaryl hydrazones is accomplished to produce tetrahydropyridazines, in which copper(II) plays dual role as a Lewis acid as well as redox catalyst. The reaction is stereospecific, and optically active cyclopropanes can be reacted with high optical purities (89-98% enantiomeric excess). The substrate scope, functional group tolerance, dual role of the copper(II) catalyst, and the use of air as an oxidant are the important practical features. A product bearing a 3-bromoaryl group can be subjected to Pd-catalyzed Suzuki coupling with boronic acid in high yield.