Cas 278183-71-4,4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile

278183-71-4

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Basic information

Product Name: 4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile
Synonyms: 4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile
CAS NO:278183-71-4
Molecular Formula:
Molecular Weight: 310.42
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile(CAS DataBase Reference)
NIST Chemistry Reference: 4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile(278183-71-4)
EPA Substance Registry System: 4-[3-(4-Amino-phenyl sulfanyl)-phenyl]-tetrahydro-pyran-4-carbonitrile(278183-71-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 278183-71-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 278183-71-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,8,1,8 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 278183-71:
(8*2)+(7*7)+(6*8)+(5*1)+(4*8)+(3*3)+(2*7)+(1*1)=174
174 % 10 = 4
So 278183-71-4 is a valid CAS Registry Number.

278183-71-4Upstream product

278183-71-4Downstream Products

950204-92-9 phenyl(4-{[3-(4-cyanotetrahydro-2H-pyran-4-yl)phenyl]thio}phenyl)carbamate

278183-71-4Relevant academic research and scientific papers

5-LIPOXYGENASE INHIBITORS

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Page/Page column 18, (2010/11/29)

The present invention relates to 5-lipoxygenase inhibitors. Compounds disclosed herein can be useful in the treatment of bronchial asthma, chronic obstructive pulmonary disorder, arthritis, type I diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, urticaria, atopic dermatitis, allergic rhinitis, other inflammatory and autoimmune diseases. Processes for the preparation of disclosed compounds, pharmaceutical compositions containing the disclosed compounds and their use as 5-lipoxygenase inhibitors are also provided.

Tetrahydropyrane derivatives as 5-lipoxygenase inhibitors

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Page/Page column 20; 21, (2010/11/28)

The present invention relates to 5-lipoxygenase inhibitors of formula I. Compounds disclosed herein can be useful in the treatment of bronchial asthma, chronic obstructive pulmonary disorder, arthritis, type 1 diabetes, multiple sclerosis, allograft rejection, psoriasis, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, urticaria, atopic dermatitis, allergic rhinitis, other inflammatory and autoimmune diseases. Processes for the preparation of disclosed compounds, pharmaceutical compositions containing the disclosed compounds and their use as 5-lipoxygenase inhibitors are also provided.

Process for preparing 5-lipoxygenase inhibitors

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, (2008/06/13)

The present invention relates to the process for preparing a compound of the formula wherein A is C1-C6alkyl, an aryl which is mono or disubstituted with F, Cl, Br, OCH3, C1-C3alkyl or benzy. In the p

Process and intermediates for preparing 5-lipoxygenase inhibitors

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, (2008/06/13)

The present invention relates to the process for preparing a compound of the formula ???wherein A is C1-C6 alkyl, an aryl which is mono or disubstituted with F, Cl , Br,, OCH3, C1-C3 alkyl or benzy. I

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