278183-97-4

Upstream product

• 278184-08-0 C₁₇H₁₉N₂O₂ 

Downstream Products

• 278184-13-7 4-(4'-ethynylphenacetylidene)-2,2,5,5-tetramethylimidazolidine-1-oxyl 
• 278183-99-6 6-(4'-ethynylbenzoyl)-2,2,4,4-tetramethylperhydroazirino[1,2-c]imidazole-3-oxyl 

Relevant academic research and scientific papers

Reactions of heterocyclic paramagnetic aldonitrone, 2,2,5,5-tetramethyl-3-imidazoline-1-oxyl 3-oxide, with alkynes

The reactions of heterocyclic paramagnetic aldonitrone, viz., 2,2,5,5-tetramethyl-3-imidazoline-1-oxyl 3-oxide, with mono- and disubstituted alkynes afford unstable isoxazoline derivatives. The reactions with monosubstituted alkynes yield predominantly 5-substituted regioisomers. The resulting isoxazoline derivatives are readily (and often spontaneously) converted into enaminoketones, viz., imidazolidine-1-oxyl derivatives. In the presence of tolan, the title paramagnetic aldonitrone gives a dimer in which one imidazoline ring undergoes profound transformation. The structure of the resulting dimer was established by X-ray diffraction analysis.