2783-12-2Relevant academic research and scientific papers
One-pot asymmetric conjugate addition-trapping of zinc enolates by activated electrophiles
Rathgeb, Xavier,March, Sebastien,Alexakis, Alexandre
, p. 5737 - 5742 (2007/10/03)
The copper-catalyzed asymmetric conjugate addition of dialkyl zinc leads to homochiral zinc enolates. These intermediates were trapped in situ with activated allylic electrophiles, without the need of additional palladium catalysis. High trans selectivity
