27877-64-1Relevant academic research and scientific papers
Low-Valent Titanium-Mediated Radical Conjugate Addition Using Benzyl Alcohols as Benzyl Radical Sources
Suga, Takuya,Shimazu, Shoma,Ukaji, Yutaka
, p. 5389 - 5392 (2018)
A concise method to directly generate benzyl radicals from benzyl alcohol derivatives has been developed. The simple and inexpensive combination of TiCl4(collidine) (collidine = 2,4,6-collidine) and manganese powder afforded a low-valent titanium reagent, which facilitated homolytic cleavage of benzylic C-OH bonds. The application to radical conjugate addition reactions demonstrated the broad scope of this method. The reaction of various benzyl alcohol derivatives with electron-deficient alkenes furnished the corresponding radical adducts.
C(sp3)-H bond functionalization with styrenesviahydrogen-atom transfer to an aqueous hydroxyl radical under photocatalysis
Mori, Shogo,Saito, Susumu
supporting information, p. 3575 - 3580 (2021/06/06)
The redox-neutral addition of α-C-H bonds of acetonitrile and acetone to styrenes was enabledviathe hydrogen-atom transfer from relatively acidic and water-miscible C(sp3)-H bonds to an aqueous hydroxyl radical generated cleanly and iteratively
