278793-03-6Relevant articles and documents
Toward catalytically active oligonucleotides: Synthesis of a flavin nucleotide and its incorporation into DNA
Schwoegler, Anja,Carell, Thomas
, p. 1415 - 1418 (2000)
(Matrix presented) The synthesis of a vitamin B2-derived flavin-nucleotide is described. A combined H-phosphonate/phosphoramidite protocol was developed for the first incorporation of flavin coenzymes into a DNA stack. The coenzyme-DNA is predi
Redoxactive oligonucleotides: Synthesis and properties of flavocoenzyme-DNA
Mees, Alexandra,Behrens, Christoph,Schwoegler, Anja,Ober, Matthias,Carell, Thomas
, p. 2670 - 2677 (2003)
The flavin heterocycle is the key component in the important and ubiquitous FMN and FAD coenzymes. As such, the flavin is able to catalyse oxygen-transfer reactions in many monooxygenases, as well as one- and two-electron transfer processes. We recently i
Synthesis of new riboflavin modified ODNs: Effect of riboflavin moiety on the G-quadruplex arrangement and stability
Romanucci, Valeria,Oliva, Rosario,Petraccone, Luigi,Claes, Sandra,Schols, Dominique,Zarrelli, Armando,Di Fabio, Giovanni
, (2020/09/15)
In the panorama of modified G-quadruplexes (G4s) with interesting proprieties, here, it has been reported the synthesis of new modified d(TGGGAG) sequences forming G-quadruplexes, with the insertion of a riboflavin unit (Rf, vitamin B2). Exploi
