27895-84-7

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 107-11-9 1-amino-2-propene 
• 1476-23-9 allylisocyanate 

Downstream Products

• 131149-02-5 diethyl allylamino(4-nitrophenyl)methanephosphonate 
• 1198108-90-5 ethyl N-allyl-N-[ethoxy-(4-nitrophenyl)methyl]carbamate 
• 89192-90-5 [1-(4-Nitro-phenyl)-meth-(E)-ylidene]-((Z)-propenyl)-amine 
• 89192-90-5 [1-(4-Nitro-phenyl)-meth-(E)-ylidene]-((E)-propenyl)-amine 
• 1418218-09-3 N-allyl-N-(4-nitrobenzyl)acrylamide 

Relevant academic research and scientific papers

Synthesis of Cyclic N-Hydroxylated Ureas and Oxazolidinone Oximes Enabled by Chemoselective Iodine(III)-Mediated Radical or Cationic Cyclizations of Unsaturated N-Alkoxyureas

In this study we describe the reactivity of unsaturated N-alkoxyureas in the presence of different combinations of a hypervalent iodine(III) reagent and a bromide source or TEMPO. Three complementary cyclizations can be achieved depending on the reaction conditions. On the one hand, PIFA with pyridinium bromide leads to an oxybromination reaction. On the other hand, bis(tert-butylcarbonyloxy)iodobenzene with tetrabutylammonium bromide or TEMPO triggers aminobromination or aminooxyamination reactions, respectively. Control experiments showed that the three reactions proceed through distinct mechanisms: the first process is ionic while the other two follow a radical manifold. (Figure presented.).

Sequential Metal-Free Thermal 1,3-Dipolar Cycloaddition of Unactivated Azomethine Ylides

The thermal 1,3-dipolar cycloaddition of unactivated azomethine ylides derived from allylamine and aromatic or heteroaromatic aldehydes with maleimides and 1,1- and 1,2-bis(phenylsulfonyl)ethylene affords endo-2,5-trans cycloadducts in moderate to good yi

Palladium-catalyzed C-H activation of N-Allyl Imines: Regioselective allylic alkylations to deliver substituted aza-1,3-dienes

A new mode of activation of an imine via a rare aza-substituted π-allyl complex is described. Palladium-catalyzed C(sp3)-H activation of the N-allyl imine and the subsequent nucleophilic attack by the α-alkyl cyanoester produced the 1-aza-1,3-d

Propylphosphonic anhydride (T3P) mediated synthesis of β-lactams from imines and aryl-substituted acetic acids

β-Lactams were prepared from imines and aryl-substituted acetic acids using T3P as an activating agent. In most cases, good to excellent yields were obtained (up to 93%) and the trans-β-lactam was the exclusive or major diastereoisomer (confirmed through

An efficient microwave method for the synthesis of imines

A large variety of aryl and heterocyclic chiral and achiral imines can be generated simply, efficiently, and cleanly through the use of microwave irradiation and the use of a small amount of molecular sieve. Reactions are rapid and complete in a matter of minutes, and can be quantitative, reducing significantly the time and amount of solvents used in compound isolation and purification.

Synthesis of nitrogen-containing heterocycles via ring-closing ene-ene and ene-yne metathesis reactions: An easy access to 1- and 2-benzazepine scaffolds and five- and six-membered lactams

Novel regioselective ring closing ene-yne metathesis provided an efficient access to different substituted 1-benzazepine scaffolds. The reported synthetic approach could also be used as a powerful tool for the selective formation of a highly functionaliza

Enantioselective organocatalysis of Strecker and Mannich reactions based on carbohydrates

Efficient organocatalysts for enantioselective Strecker and Mannich reactions were constructed from glucosamine as a readily accessible chiral scaffold. A variety of aromatic aldimines were subjected to hydrocyanation with good to excellent yield (72-98%)

SYNTHESIS AND REACTIONS OF TRIPHENYLARSINIMINES

Triphenylarsinimines formed in situ from isocyanates and triphenylarsine oxide have been found to react smoothly with carbonyl compounds like aldehydes, quinones and aromatic ketones giving the corresponding Schiff's bases in high yields.In the case of aldehydes, quinones or activated ketones, e.g., α-diketones, only a catalytic amount of triphenylarsine oxide is necessary for the reaction to proceed to completion.Quinones react with particular ease.Thus the previously unknown 9,10-phenanthrenequinone N-phenylimine 12 (R = Ph, Scheme IV) can be prepared in high yield from 9,10-phenanthrenequinone and phenyl isocyanate under catalytic influence of triphenylarsine oxide.Orthoquinones like 9,10-phenanthrenequinone react with vinylic isocyanates, forming monoimines 13 which rearrange to 1,4-oxazines 14 (Scheme V).Diisocyanates react under the catalytic action of triphenylarsine oxide with dialdehydes under mild conditions, forming some interesting new polymers 25, 26 in high yields.Reactions with aliphatic isocyanates give N-alkyl-N'-arylcarbodiimides, whereas reactions with isothiocyanates proceed through intermediates 20 and 21 to mixed carbodiimides 16, 24 and 25. Key words: Triphenylarsinimines; synthesis; reactions; Schiff's bases; unsymmetrical carbodiimides; polymers.

Synthesis of organophosphorus compounds via silyl esters of phosphorous acids

The addition of trimethylsilyloxy phosphorus (III)derivatives generated in situ to imines at room temperature provides a mild selective and high yielding route to α-aminoalkylphosphorate and α-aminoalkylphenylphosphinate esters. Isocyanates and carbodiimides react similarly to give phosphonoureas and phosphonoguarnidines respectively aldehydes and ketones are much less reactive and cyanides are inert.