27914-56-3

Usage

Uses

Used in Research and Pharmaceutical Industries:
4-(2,2,2-trifluoroethoxy)benzoic acid is used as a building block for the synthesis of various organic compounds, contributing to the development of new pharmaceuticals and other chemical products.
Used in Agrochemical Production:
In the agrochemical industry, 4-(2,2,2-trifluoroethoxy)benzoic acid is utilized in the production of herbicides and pesticides. Its chemical stability and hydrophobic properties make it an effective component in these formulations, enhancing their performance and efficacy in controlling weeds and pests.

Upstream product

• 36844-44-7 ethyl 4-(2,2,2-trifluoroethoxy)benzoate 
• 696-63-9 4-Methoxybenzenethiol 
• 129560-87-8 4-(1,1-dihydroperfluorooctyloxy)benzoic acid 
• 4619-85-6 4-hexylbenzenethiol 
• 129590-24-5 4-(1,1-dihydroperfluorobutyloxy)benzoic acid 
• 555-16-8 4-nitrobenzaldehdye 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 76579-46-9 4-(2,2,2-trifluoroethoxy)benzaldehyde 

Downstream Products

• 27914-55-2 C₂₅H₂₈F₆N₂O₄ 
• 128140-40-9 4-(2,2,2-Trifluoro-ethoxy)-benzoic acid 4-ethoxy-phenyl ester 
• 110855-51-1 1-Isocyanato-4-(2,2,2-trifluoro-ethoxy)-benzene 
• 155432-23-8 1-[4-(2,2,2-trifluoroethoxy)phenyl]-5(1H,4H)-tetrazolone 
• 155432-24-9 1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-4-[4-(2,2,2-trifluoroethoxy)phenyl]-5(1H,4H)-tetrazolone 
• 50778-60-4 4-(2',2',2'-Trifluoroethoxy)benzamide 
• 1346614-63-8 spiro[benzo[b]pyrrolo[1,2-d][1,4]oxazine-4,4'-piperidine]-1'-yl(4-(2,2,2-trifluoroethoxy)phenyl)methanone 
• 35554-38-2 methyl 4-(2,2,2-trifluoroethoxy)-benzoate 
• 1192829-76-7 3-chloro-4-(2,2,2-trifluoroethoxy)benzoic acid 
• 864178-59-6 3-chloro-4-(2,2,2-trifluoro-ethoxy)-benzoic acid methyl ester 

Relevant academic research and scientific papers

The flocculated acryloyldimethyltauric molecule ligand

Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.

Optically active antifungal azoles. VI. Synthesis and antifungal activity of N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl) propyl]-N′-(4-substituted phenyl)-3(2H,4H)-1,2,4-triazolones and 5(1H,4H)-tetrazolones

A new series of optically active antifungal azoles, N-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl) propyl]-N′-(4-substituted phenyl)-3(2H,4H)-1,2,4-triazolones (1,2) and 5(1H,4H)-tetrazolones (3), were prepared from the triflate derivative of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol (13) by an SN2 displacement reaction with the union of an azolone (17-19) and subsequent ring-opening reaction with 1H-1,2,4-triazole. The optically active oxiranylethanol 13 was synthesized from methyl (R)-lactate in a stereocontrolled manner. The azolones 1-3 prepared showed potent antifungal activities in vitro and in vivo.

Achiral fluorine-containing liquid crystals

Achiral fluorine-containing liquid crystal compounds are provided. The compounds comprise a fluorocarbon terminal portion and a hydrocarbon or another fluorocarbon terminal portion, the terminal portions being connected by a central core, the compounds having smectic mesophases or having latent smectic mesophases. The compounds are useful in liquid crystal display devices both along and in mixtures with other materials. Also provided is a process for preparing these compounds.

Liquid Crystals with Polar Substituents Containing Fluorine: Synthesis and Physical Properties

Liquid crystalline compounds with various polar terminal groups containing fluorine have been prepared (see below formula 1 with Z = S-CHF2, S-CF3, SO-CHF2, SO-CF3, SO2-CHF2, SO2-CF3, SO2F, OCH2CF3, CO-OCH2CF3, CO-CF3, CO-CF2Cl, CO-CF2H, CO-CF2-CH3, CO-CF2-C3H7).The synthesis of these compounds is outlined here and their physical properties (phase transitions, dielectric anisotropy, birefringence, viscosity) are discussed.