27917-11-9

Usage

Uses

Used in Pharmaceutical Industry:
4-CHLORO-2-METHYLBENZYLAMINE is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows it to be a key component in the creation of molecules with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4-CHLORO-2-METHYLBENZYLAMINE is employed as a precursor in the production of agrochemicals, such as pesticides and herbicides. Its role in these applications is to provide the necessary structural elements for the active ingredients to effectively control, repel, or kill unwanted organisms in agricultural settings.
Used in Organic Synthesis:
4-CHLORO-2-METHYLBENZYLAMINE is utilized as a building block in organic synthesis for its reactivity and structural features. It is particularly valuable in the synthesis of complex organic molecules that require the presence of a chloro substituent and a methyl group on the amino function, facilitating the creation of a diverse range of chemical compounds.
Safety Note:
Due to its flammable nature, 4-CHLORO-2-METHYLBENZYLAMINE should be handled with care, adhering to proper safety protocols to prevent accidents and ensure the safety of personnel and the environment.

InChI:InChI=1/C8H10ClN/c1-6-4-8(9)3-2-7(6)5-10/h2-4H,5,10H2,1H3

Upstream product

• 900505-06-8 2-(4-chloro-2-methyl-benzyl)-isoindole-1,3-dione 
• 40137-29-9 2-methyl-4-chlorobenzaldehyde 
• 129716-11-6 2-methyl-4-chlorobenzyl alcohol 

Downstream Products

• 900505-19-3 4-(4-chloro-2-methyl-benzyl)-3-(4-chloro-phenyl)-7-iodo-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione 
• 1194839-27-4 C₁₉H₂₆ClNO₃ 
• 1227946-46-4 3-[5,6-bis(methyloxy)-2-pyridinyl]-N-[(4-chloro-2-methylphenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydrothieno[3,2-d]pyrimidine-6-carboxamide 
• 1202705-85-8 7-{[(4-chloro-2-methylphenyl)methyl]amino}-2,2-dimethyl-4H,5H-pyrano[4,3-d][1,3]dioxin-4,5-dione 

Relevant academic research and scientific papers

THERAPEUTIC INHIBITORY COMPOUNDS

The invention provides compounds of Formula I and Formula II: A-B-C-D-E-F-G-J (I) C-D-E-F-G-J (II) wherein A, B, C, D, E, F, G, and J have any of the values defined in the specification, and salts thereof. The compounds are useful for inhibiting plasma kallikrein, and for treating a disease or condition in an animal where inhibition of plasma kallikrein is indicated.

Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity

The disruption of the p53-Hdm2 protein-protein interaction induces cell growth arrest and apoptosis. We have identified the 1,4-benzodiazepine-2,5-dione scaffold as a suitable template for inhibiting this interaction by binding to the Hdm2 protein. Several compounds have been made with improved potency, solubility, and cell-based activities.