279227-04-2

Basic information

• Product Name: 3-Nonanone, 2-[(4S)-2,2-dimethyl-1,3-dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-9-(phenyl methoxy)-, (4R,5S,6S)-
• CAS NO: 279227-04-2
• Molecular Formula: C25H40O5
• Molecular Weight: 420.59
• Mol File: 279227-04-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Nonanone, 2-[(4S)-2,2-dimethyl-1,3-dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-9-(phenyl methoxy)-, (4R,5S,6S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Nonanone, 2-[(4S)-2,2-dimethyl-1,3-dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-9-(phenyl methoxy)-, (4R,5S,6S)-(279227-04-2)
• EPA Substance Registry System: 3-Nonanone, 2-[(4S)-2,2-dimethyl-1,3-dioxan-4-yl]-5-hydroxy-2,4,6-trimethyl-9-(phenyl methoxy)-, (4R,5S,6S)-(279227-04-2)

Safety Data

• Hazardous Substances Data: 279227-04-2(Hazardous Substances Data)

Upstream product

• 250679-51-7 (3S)-1-[(1S,5R)-10,10-dimethyl-3,3-dioxido-3-thia-4-azatricyclo[5.2.1.0^1.5]dec-4-yl]-3-hydroxy-4,4-dimethylheptan-1,5-dione 
• 250679-54-0 (4S)-4-benzyl-3-[(2S)-5-(benzyloxy)-2-methylpentanoyl]-1,3-oxazolan-2-one 
• 250679-52-8 (3S)-3-[((tert-butyl)dimethylsilyl)oxy]-1-[(1S,5R)-10,10-dimethyl-3,3-dioxido-3-thia-4-azatricyclo[5.2.1.0^1.5]dec-4-yl]-4,4-dimethylheptan-1,5-dione 
• 250679-53-9 (5S)-5-{[(tert-butyl)dimethylsilyl]oxy}-7-hydroxy-4,4-dimethylheptan-3-one 
• 187283-45-0 (S)-3-((tert-butyldimethylsilyl)oxy)-4,4-dimethyl-5-oxoheptanoic acid 
• 106921-60-2 2,2-dimethyl-3-oxopentanal 
• 81678-40-2 (2S)-5-(benzyloxy)-2-methylpentan-1-ol 
• 185148-95-2 2-[(4S)-2,2-dimethyl-1,3-dioxan-4-yl]-2-methyl-3-pentanon 
• 279227-20-2 (2S)-5-benzyloxy-2-methyl-1-pentanal 

Downstream Products

• 279227-06-4 (3S,6R,7S,8S)-11-(benzyloxy)-1,3,7-tris{[(tert-butyl)dimethylsilyl]oxy}-4,4,6,8-tetramethylundecan-5-one 
• 279227-09-7 (3S,6R,7S,8S)-11-(benzyloxy)-3,7-bis{[(tert-butyl)dimethylsilyl]oxy}-4,4,6,8-tetramethyl-5-oxoundecanoic acid 
• 279227-10-0 (3S,6R,7S,8S)-11-(benzyloxy)-3,7-bis{[(tert-butyl)dimethylsilyl]oxy}-4,4,6,8-tetramethyl-5-oxoundecanoic acid methyl ester 
• 279227-07-5 (3S,6R,7S,8S)-11-(benzyloxy)-3,7-bis{[(tert-butyl)dimethylsilyl]oxy}-hydroxy-4,4,6,8-tetramethylundecan-5-one 
• 279227-08-6 (3S,6R,7S,8S)-11-(benzyloxy)-3,7-bis{[(tert-butyl)dimethylsilyl]oxy}-4,4,6,8-tetramethyl-5-oxoundecanal 
• 279227-05-3 (3S,6R,7S,8S)-11-(benzyloxy)-1,3,7-trihydroxy-4,4,6,8-tetramethylundecan-5-one 

Relevant articles and documents

Synthesis and biological evaluation of highly potent analogues of Epothilones B and D

A series of new epothilone B and D analogues incorporating fused hetero-aromatic side chains have been prepared. The synthetic strategy is based on olefin 3 as the common intermediate and allows variation of the side-chain structure in a highly convergent and stereoselective manner. Epothilone analogues 1a-d and 2a-d are more potent inhibitors of cancer cell proliferation than the corresponding parent epothilones B orD. (C) 2000 Elsevier Science Ltd.