279236-97-4

Upstream product

• 173774-50-0 N-Boc-piperazine-2-amidoanhydride 
• 112086-52-9 N-benzyl-3-(1H-imidazol-1-yl)propan-1-amine 

Downstream Products

• 281197-79-3 N₂-[3-(1H-imidazol-1-yl)propyl]-N₂,4-bis(phenylmethyl)-1,2(R)-piperazinecarboxamide 
• 281197-80-6 N₂-[3-(1H-imidazol-1-yl)propyl]-N₁,2,4-tris(phenylmethyl)-1,2(R)-piperazinecarboxamide 

Relevant academic research and scientific papers

NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl-protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.

Inhibitors of farnesyl-protein transferase

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.