279263-10-4

Basic information

• Product Name: 4-ETHOXY-3-FLUOROPHENYLBORONIC ACID
• Synonyms: AKOS BRN-0575;4-ETHOXY-3-FLUOROBENZENEBORONIC ACID;4-ETHOXY-3-FLUOROPHENYLBORONIC ACID;3-FLUORO-4-ETHOXYBENZENEBORONIC ACID;4-Ethoxy-3-Fluorophenylboronic;4-Borono-2-fluorophenetole;4-Ethoxy-3-fluorophenylboronic Acid (contains varying amounts of Anhydride)
• CAS NO: 279263-10-4
• Molecular Formula: C₈H₁₀BFO₃
• Molecular Weight: 183.97
• Product Categories: blocks;BoronicAcids;FluoroCompounds;Aryl;Boronic acid;Organoborons;Boronic Acids;Boronic Acids and Derivatives;Boronic Acids
• Mol File: 279263-10-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 108-113 C
• Boiling Point: 328.119 °C at 760 mmHg
• Flash Point: 152.241 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.501
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Methanol
• PKA: 7.90±0.10(Predicted)
• CAS DataBase Reference: 4-ETHOXY-3-FLUOROPHENYLBORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHOXY-3-FLUOROPHENYLBORONIC ACID(279263-10-4)
• EPA Substance Registry System: 4-ETHOXY-3-FLUOROPHENYLBORONIC ACID(279263-10-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 279263-10-4(Hazardous Substances Data)

Usage

Uses

suzuki reaction

InChI:InChI=1/C8H10BFO3/c1-2-13-8-4-3-6(10)5-7(8)9(11)12/h3-5,11-12H,2H2,1H3

Upstream product

• 2105-94-4 4-bromo-2-fluorophenol 
• 121-43-7 Trimethyl borate 
• 115467-08-8 3-fluoro-4-ethoxy bromobenzene 

Downstream Products

• 1429499-93-3 (4S)-6-(4-ethoxy-3-fluorophenyl)-4-(1H-imidazol-4-ylmethyl)-7-[3-(trifluoromethoxy)phenyl]-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one 
• 98121-48-3 4-ethoxy-3-fluorophenol 

Relevant articles and documents

LIQUID CRYSTALLINE COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY HAVING FLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT

PROBLEM TO BE SOLVED: To provide a liquid crystalline compound exhibiting high stability against heat or light, high clearing point (or high upper limit temperature), low lower limit temperature of a liquid crystal phase, low viscosity, appropriate optical anisotropy, negative large dielectric constant anisotropy, appropriate elastic modulus, and excellent compatibility with other liquid crystalline compounds at a room temperature or a low temperature, and to provide a liquid crystal composition containing the compound and a liquid crystal display element containing the composition. SOLUTION: There is provided a compound represented by the formula (1). R1 is alkyl having 2 to 10 carbon atoms, in which one -CH2CH2- is substituted by -CH=CH-, or the like; R2 is alkyl having 1 to 8 carbon atoms, a ring A1 is 1,4-cyclohexylene or the like, Y1 and Y2 are hydrogen, fluorine or the like, Z1 is a single bond or the like; n1 is 1 or 2. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

BENZENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY

Known compounds showing negative dielectric anisotropy show negative dielectric anisotropy of relatively large values but are not satisfactory in view of the balance of the physical property as the liquid crystal material such as having low clearing point and showing high viscosity. The present invention intends to provide a liquid crystalline compound showing a negative dielectric anisotropy, as well as having excellent balance for physical property such as having relatively high clearing point, relatively low viscosity, appropriate optical anisotropy, and excellent compatibility with other liquid crystalline compounds. The compound of the invention is a compound represented by Formula (1) or Formula (2). In the formulae, Ra and Rb each independently is hydrogen or alkyl of 1 to 20 carbon atoms, A 1 , A 11 , A 12 , A 2 , A 21 and A 22 each independently is a cyclic group, Y, W, Z 11 , Z 12 , Z 2 , Z 21 and Z 22 each independently is a bonding group, and j, k, m, n, p and q each independently is 0 or 1 and the sum of them is 1, 2 or 3;