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4-BROMO-1-ETHOXY-2-FLUOROBENZENE is a chemical compound with the molecular formula C8H8BrFO. It is a derivative of benzene with a bromine atom, an ethoxy group, and a fluorine atom attached to the carbon ring. 4-BROMO-1-ETHOXY-2-FLUOROBENZENE is commonly used in organic synthesis and pharmaceutical research as a building block for creating more complex molecules. It is important to handle 4-BROMO-1-ETHOXY-2-FLUOROBENZENE with caution, as it may be harmful if ingested, inhaled, or absorbed through the skin, and exposure should be minimized to prevent potential health risks.

115467-08-8

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115467-08-8 Usage

Uses

Used in Organic Synthesis:
4-BROMO-1-ETHOXY-2-FLUOROBENZENE is used as a building block for the synthesis of more complex organic molecules. Its unique structure allows for various chemical reactions, making it a valuable component in the creation of new compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 4-BROMO-1-ETHOXY-2-FLUOROBENZENE is used as a starting material for the development of new drugs. Its presence in the molecular structure can influence the properties and effectiveness of the final drug product, making it an important component in drug discovery and design.
Used in Chemical Research:
4-BROMO-1-ETHOXY-2-FLUOROBENZENE is also used in academic and industrial research settings to study the properties and reactions of halogenated aromatic compounds. Understanding the behavior of such compounds can lead to advancements in various fields, including materials science and catalysis.

Check Digit Verification of cas no

The CAS Registry Mumber 115467-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,5,4,6 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 115467-08:
(8*1)+(7*1)+(6*5)+(5*4)+(4*6)+(3*7)+(2*0)+(1*8)=118
118 % 10 = 8
So 115467-08-8 is a valid CAS Registry Number.

115467-08-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromo-1-ethoxy-2-fluorobenzene

1.2 Other means of identification

Product number -
Other names 4-bromo-1-ethoxy-2-fluoro-benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:115467-08-8 SDS

115467-08-8Relevant articles and documents

LIQUID CRYSTALLINE COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY HAVING FLUOROBIPHENYL, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT

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Paragraph 0138; 0139, (2019/04/26)

PROBLEM TO BE SOLVED: To provide a liquid crystalline compound exhibiting high stability against heat or light, high clearing point (or high upper limit temperature), low lower limit temperature of a liquid crystal phase, low viscosity, appropriate optical anisotropy, negative large dielectric constant anisotropy, appropriate elastic modulus, and excellent compatibility with other liquid crystalline compounds at a room temperature or a low temperature, and to provide a liquid crystal composition containing the compound and a liquid crystal display element containing the composition. SOLUTION: There is provided a compound represented by the formula (1). R1 is alkyl having 2 to 10 carbon atoms, in which one -CH2CH2- is substituted by -CH=CH-, or the like; R2 is alkyl having 1 to 8 carbon atoms, a ring A1 is 1,4-cyclohexylene or the like, Y1 and Y2 are hydrogen, fluorine or the like, Z1 is a single bond or the like; n1 is 1 or 2. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

New pyrrolidine derivatives, pharmaceutical compositions and uses thereof

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Paragraph 0411, (2014/04/18)

Pyrrolidine derivatives of the formula and their use as medicaments for the treatment of obesity and type 2 diabetes.

LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT

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Page/Page column 43-44, (2012/08/14)

The invention provides a liquid crystal compound having general physical properties necessary for the liquid crystal compound, namely, stability to heat, light and so forth, a small viscosity, a refractive index anisotropy having a suitable magnitude value, a dielectric anisotropy having a suitable magnitude value, steep electrooptical characteristics, a wide temperature range of a nematic phase, and an excellent compatibility with other liquid crystal compounds, in particular, a liquid crystal compound having a wide temperature range of the nematic phase; a compound represented by formula (i): wherein, for example, R1 and R2 are alkyl having 1 to 8 carbons or alkenyl having 2 to 8 carbons; ring A1 is trans-1,4-cyclohexylene or 1,4-phenylene; ring A2 is trans-1,4-cyclohexylene or 2,3-difluoro-1,4-phenylene; Q1 and Q2 are fluorine or chlorine; and h is 0, 1 or 2.

CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS

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Page/Page column 272, (2009/03/07)

The present invention relates to compounds of formula (I) for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.

BENZOCHROMENE DERIVATIVES

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Page/Page column 129, (2010/02/08)

The invention relates to benzochromene derivatives of formula (I), in which the different parameters have the meanings as cited in the text, to liquid crystal media, which contain these compounds, and to the use of these media in electro-optical displays,

Potent, novel in vitro inhibitors of the Pseudomonas aeruginosa deacetylase LpxC

Kline, Toni,Andersen, Niels H.,Harwood, Eric A.,Bowman, Jason,Malanda, Andre,Endsley, Stephanie,Erwin, Alice L.,Doyle, Michael,Fong, Susan,Harris, Alex L.,Mendelsohn, Brian,Mdluli, Khisimuzi,Raetz, Christian R. H.,Stover, C. Kendall,Witte, Pamela R.,Yabannavar, Asha,Zhu, Shuguang

, p. 3112 - 3129 (2007/10/03)

Deacetylation of uridyldiphospho-3-O-(R-hydroxydecanoyl)-N-acetylglucosamine by LpxC is the first committed step in the Pseudomonas aeruginosa biosynthetic pathway to lipid A; homologous enzymes are found widely among Gram-negative bacteria. As an essential enzyme for which no inhibitors have yet been reported, the P. aeruginosa LpxC represents a highly attractive target for a novel antibacterial drug. We synthesized several focused small-molecule libraries, each composed of a variable aromatic ring, one of four heterocyclic/spacer moieties, and a hydroxamic acid and evaluated the LpxC inhibition of these compounds against purified P. aeruginosa enzyme. To ensure that the in vitro assay would be as physiologically relevant as possible, we synthesized a tritiated form of the specific P. aeruginosa glycolipid substrate and measured directly the enzymatically released acetate. Several of our novel compounds, predominantly those having fluorinated substituents on the aromatic ring and an oxazoline as the heterocyclic moiety, demonstrated in vitro IC50 values less than 1 μM. We now report the synthesis and in vitro evaluation of these P. aeruginosa LpxC inhibitors.

Insecticidal ethers

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, (2008/06/13)

This invention relates to novel fluorinated ethers, useful as insecticides and acaricides, to processes and intermediates for their preparation, to insecticidal and acaricidal compositions thereof and to methods of combating and controlling insect and acarine pests therewith.

Diphenyl ether derivatives and their use as insecticides

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, (2008/06/13)

A compound of formula: STR1 wherein W represents one or more substituents selected from halo, alkyl, alkoxy, alkoxyalkyl, haloalkyl and haloalkoxy or W represents a bidentate group linking adjacent carbon atoms selected from alkylene and alkylenedioxy; Y is a group of formula STR2 wherein X is a group of formula --(CF2)n R3, where R3 is selected from hydrogen, chloro and fluoro, and n is one or two, R1 is selected from hydrogen, chloro, fluoro and hydroxy and R2 is selected from methyl, cyano, ethynyl and hydrogen; Q is selected from carbon bearing a hydrogen atom and nitrogen; and Z represents one or more substituents selected from fluoro, benzyl, phenoxy, chlorophenoxy, fluorophenoxy and bromophenoxy, or any isomer thereof. Processes for preparing these compounds and intermediates for use therein, insecticidal compositions containing these compounds and the use thereof are also disclosed.

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