27952-00-7

Basic information

• Product Name: (E)-2-(4-bromostyryl)pyridine
• Synonyms: (E)-2-(4-bromostyryl)pyridine
• CAS NO: 27952-00-7
• Molecular Formula: C13H10BrN
• Molecular Weight: 260.133
• Mol File: 27952-00-7.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (E)-2-(4-bromostyryl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(4-bromostyryl)pyridine(27952-00-7)
• EPA Substance Registry System: (E)-2-(4-bromostyryl)pyridine(27952-00-7)

Safety Data

• Hazardous Substances Data: 27952-00-7(Hazardous Substances Data)

Usage

Description

(E)-2-(4-bromostyryl)pyridine, with the molecular formula C12H9BrN, is a chemical compound derived from pyridine. It features a bromine atom and a styryl group, which may contribute to its chemical and biological properties. (E)-2-(4-bromostyryl)pyridine holds potential for use in organic synthesis and pharmaceutical research, serving as an intermediate in the production of other chemicals or as a building block for more complex compounds.

Uses

Used in Organic Synthesis:
(E)-2-(4-bromostyryl)pyridine is used as an intermediate in the synthesis of various chemicals. Its unique structure, including the bromine and styryl groups, allows for further chemical reactions and modifications, making it a valuable component in creating a range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (E)-2-(4-bromostyryl)pyridine is used as a building block for the synthesis of more complex compounds with potential medicinal properties. Its structural features may contribute to the development of new drugs or drug candidates, particularly those targeting specific biological pathways or receptors.

Upstream product

• 38700-15-1 triphenyl-(2-pyridylmethyl)phosphonium chloride 
• 1122-91-4 4-bromo-benzaldehyde 
• 4377-33-7 2-chloromethylpyridine 
• 109-06-8 α-picoline 
• 873-75-6 4-bromobenzenemethanol 
• 100-69-6 2-vinylpyridine 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 1121-60-4 pyridine-2-carbaldehyde 
• 38186-51-5 diethyl (4-bromobenzyl)phosphonate 
• 589-17-3 p-bromobenzyl chloride 

Downstream Products

• 1071795-01-1 2-[2-(4-bromophenyl)ethynyl]pyridine 

Relevant articles and documents

A new insight into the push-pull effect of substituents via the stilbene-like model compounds

In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi

Borane-Catalyzed Chemoselective and Enantioselective Reduction of 2-Vinyl-Substituted Pyridines

Herein, we report that highly chemoselective and enantioselective reduction of 2-vinyl-substituted pyridines has been achieved for the first time. The reaction, which uses chiral spiro-bicyclic bisboranes as catalysts and HBpin and an acidic amide as reducing reagents, proceeds through a cascade process involving 1,4-hydroboration followed by transfer hydrogenation of a dihydropyridine intermediate. The retained double bond in the reduction products permits their conversion to natural products and other useful heterocyclic compounds by simple transformations.

NOVEL HYDRAZIDE CONTAINING COMPOUNDS AS BTK INHIBITORS

The present invention relates to novel hydrazide containing compounds as Bruton tyrosine kinase inhibitors, process of preparation thereof, and to the use of the compounds in the preparation of pharmaceutical compositions for the therapeutic treatment of disorders involving mediation of Bruton tyrosine kinase in humans.