27958-05-0

Upstream product

• 27958-06-1 (2R,3S,4S)-3,4-dihydroxy-2-(4-methoxybenzyl)pyrrolidine 
• 501-53-1 benzyl chloroformate 
• 23006-20-4 (3R,4S,5R)-N-Benzyl-3,4-dihydroxy-5-p-anisyl-pyrrolidon-2 
• 165560-20-3 (2R,3S,4S)-N-tert-butoxycarbonyl-3,4-bis(tert-butyldimethylsilyloxy)-2-trityloxymethylpyrrolidine 
• 165560-22-5 (2R,3S,4S)-N-tert-butoxycarbonyl-3,4-dibenzyloxy-2-trityloxymethylpyrrolidine 
• 165560-13-4 1,1-dimethylethyl N-<(1R,2S,3R)-2,3-bis(tert-butyldimethylsilyloxy)-3-methoxycarbonyl-1-trityloxymethylpropanyl>carbamate 
• 165560-21-4 (2R,3S,4S)-N-tert-butoxycarbonyl-3,4-dihydroxy-2-trityloxymethylpyrrolidine 
• 127298-72-0 (2R,3S,4S)-N-benzyl-3,4-bis(benzyloxy)-2-hydroxymethylpyrrolidine 
• 172330-70-0 (3R,4S,5S)-1-Benzyl-3,4-bis-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyl)-pyrrolidin-2-one 
• 1054695-76-9 (2S,3S,4S,5R)-5-Benzylamino-1,3,4-tris-benzyloxy-6-(4-methoxy-phenyl)-hexan-2-ol 
• 172330-68-6 (3R,4S,5R)-1-Benzyl-3,4-bis-benzyloxy-5-(4-methoxy-benzyl)-pyrrolidin-2-one 

Downstream Products

• 100449-59-0 (2R,3S,4S)-N-(benzyloxycarbonyl)-3-hydroxy-2-(4-methoxybenzyl)-4-<(tert-butyldimethylsilyl)oxy>pyrrolidine 

Relevant academic research and scientific papers

SYNTHESIS OF (2R,3R,4R,5R)-3,4-DIHYDROXY-2,5-DIHYDROXYMETHYLPYRROLIDINE AND (-)-ANISOMYCIN DERIVATIVE FROM (S)-PYROGLUTAMIC ACID DERIVATIVE

Double asymmetric dihydroxylation of (E)-α,β-unsaturated ester (2) with a catalitic amount of potassium osmate and chiral ligand gave dihydroxy compounds (3a and 4a) selectively.Polyhydroxylated pyrrolidines (10 and 14) were synthesized from corresponding methoxymethyl ether (3c) and tert-butyl-dimethylsilyl ether (4d), respectively.

A SHORT SYNTHETIC APPROACH TO ENANTIOMERICALLY PURE (-)-ANISOMYCIN

A convenient enantiomerically pure route to an antibiotic, natural (-)-anisomycin has been developed in a short number of steps by featuring the stereocontrolled elaboration of the fuctionalized homochiral lactam derived from 2,3,5-tri-O-benzyl-β-L-arabin