279669-90-8

Upstream product

• 65005-14-3 1,4-dioxa-spiro[4.5]decane-7-carbaldehyde 
• 555-16-8 4-nitrobenzaldehdye 
• 279669-88-4 diethyl 2-oxo-6-(4-tritylamino)phenylhexylphosphonate 
• 104498-78-4 5-(4-Amino-phenyl)-pentanoic acid methyl ester 
• 279669-89-5 (E)-1-(1,4-Dioxa-spiro[4.5]dec-7-yl)-7-[4-(trityl-amino)-phenyl]-hept-1-en-3-one 
• 279669-87-3 5-[4-(trityl-amino)-phenyl]-pentanoic acid methyl ester 

Downstream Products

• 279669-91-9 3-[(E)-7-(4-Amino-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-92-0 3-[(E)-7-(4-Azido-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-93-1 3-[(E)-7-(4-Amino-3-iodo-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-94-2 3-[(E)-7-(4-Azido-3-iodo-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 

Relevant academic research and scientific papers

Leukotriene B4 photoaffinity probes: design, synthesis and evaluation of new arylazide-1,3-disubstituted cyclohexanes.

The synthesis and the binding affinities of new leukotriene B4 receptor photoaffinity probes, where a 1,3-disubstituted cyclohexane ring replaces the conjugated delta6,7 and delta8,9 double bonds of the natural eicosanoid, are described. One enantiomeric compound, 4b alpha, is specifically cross-linked upon photolysis to the recombinant leukotriene B4 receptor from human origin (h-BLTR) solubilized in a micellar medium. This probe appears as a good candidate for identifying the ligand binding site of this receptor.