65005-14-3

Usage

Type of compound

Cyclic organic compound

Structural feature

Contains a spiro ring system

Functional group

Carboxaldehyde

Common uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals, reagent in organic synthesis, flavoring agent in the food industry

Physical state

Colorless liquid

Odor

Pleasant

Stability

Relatively stable under normal conditions

Safety

Hazardous if not used properly, should be handled with care

Upstream product

• 13149-16-1 methyl 1,4-dioxaspiro[4.5]decane-7-carboxylate 
• 19438-10-9 methyl 3-hydroxybenzoate 
• 21531-47-5 3-oxo-cyclohexanecarboxylic acid methyl ester 
• 37722-82-0 methyl 3-hydroxycyclohexanecarboxylate 
• 1740-63-2 3-vinylcyclohexanone 
• 1312080-15-1 7-vinyl-1,4-dioxaspiro[4.5]decane 
• 930-68-7 cyclohexenone 

Downstream Products

• 279669-91-9 3-[(E)-7-(4-Amino-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-92-0 3-[(E)-7-(4-Azido-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-93-1 3-[(E)-7-(4-Amino-3-iodo-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-94-2 3-[(E)-7-(4-Azido-3-iodo-phenyl)-3-hydroxy-hept-1-enyl]-cyclohexanone 
• 279669-90-8 (E)-1-(1,4-Dioxa-spiro[4.5]dec-7-yl)-7-[4-(trityl-amino)-phenyl]-hept-1-en-3-ol 
• 183872-09-5 3-[(E)-3-tert-butyldimethylsilyloxy-oct-1-en-1-yl]cyclohexanone 
• 183872-08-4 3-((E)-3-Hydroxy-oct-1-enyl)-cyclohexanone 

Relevant academic research and scientific papers

Construction of AE ring system for the C19-diterpenoid alkaloids with a 5β-hydroxyl group

An AE azabicyclic fragment, with a β-hydroxyl group at C-5 and a substituent at C-1, of the C19-diterpenoid alkaloids, was synthesized. The key reactions include an intramolecular Claisen-type condensation, double Mannich reaction, and stereose

Synthesis and structure-activity relationships of new 1,3- disubstituted cyclohexanes as structurally rigid leukotriene B4 receptor antagonists

A series of 1-hydroxy-3-[3-hydroxy-7-phenyl-1-hepten-1-yl] cyclohexane acetic acid derivatives was designed based on postulated active conformation of leukotriene B4 (LTB4) and evaluated as human cell surface LTB4 receptor