279685-83-5Relevant academic research and scientific papers
Enantioselective synthesis of protected cyanohydrins
Veum, Lars,Kuster, Marina,Telalovic, Selvedin,Hanefeld, Ulf,Maschmeyer, Thomas
, p. 1516 - 1522 (2007/10/03)
A straightforward process for the preparation of optically active protected cyanohydrins, important building blocks for the synthesis of drugs and agrochemicals, has been established. Lipase B from Candida Antarctica (CAL-B) catalysed the kinetic resoluti
An enantioselective synthesis of the Williams glycine template
Van Den Nieuwendijk,Warmerdam,Brussee,Van Der Gen
, p. 801 - 806 (2007/10/02)
The Williams glycine template for amino acid synthesis, benzyl (2R,3S)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (1), was prepared in enantiomerically pure form in six steps from benzaldehyde in 48% overall yield. The initial chirality of the molecule wa
