27983-93-3Relevant articles and documents
New synthesis of 2-methyleneaziridines and 2-methyleneazetidines by dimethyl titanocene mediated methylenation of α- and β-lactams
Abbaspour Tehrani, Kourosch,De Kimpe, Norbert
, p. 1975 - 1978 (2007/10/03)
2-Methyleneaziridines and 2-methyleneazetidines were synthesized via a titanium mediated olefination procedure starting from the corresponding α- lactams and β-lactams. (C) 2000 Elsevier Science Ltd.
A Convenient Synthesis of 4-Unsubstituted β-Lactams
Overman, Larry E.,Osawa, Tatsushi
, p. 1698 - 1701 (2007/10/02)
The reaction of lithium ester enolates with N-(cyanomethyl)amines affords 4-unsubstituted β-lactams in good yields, see eq 1.The N-1 substituent can be varied widely, as can the C-3 substituents, which can be H, alkyl, SPh, NH2, or NHCOR.The preparation o
A one-pot synthesis of β-lactams by the reaction of β-haloacyl chlorides with α-amino acids
Okawara,Matsuda,Noguchi,Furukawa
, p. 1574 - 1578 (2007/10/02)
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