280-75-1 Usage
Uses
Used in Pharmaceutical Industry:
Pyridine is used as a precursor for the synthesis of various pharmaceuticals, contributing to the development of essential medications due to its ability to form stable compounds with a wide range of functional groups.
Used in Pesticide Industry:
In the pesticide industry, pyridine is utilized as a precursor for the production of agrochemicals, playing a crucial role in the creation of effective pest control agents.
Used in Dye Industry:
Pyridine is employed as a precursor in the synthesis of dyes, enabling the production of a diverse array of colorants for various applications.
Used in Rubber and Agrochemical Production:
Pyridine serves as a building block in the production of rubber chemicals and other industrial chemicals, including agrochemicals, where it is instrumental in developing compounds that enhance crop protection and yield.
Used as a Solvent:
Pyridine is widely used as a solvent in various chemical processes, providing a medium for reactions that require its unique solvency properties.
Used as a Denaturant:
In the context of antifreeze, pyridine is used as a denaturant, modifying the properties of the product to make it unsuitable for consumption while maintaining its functional use in industrial applications.
Used as a Reagent in Organic Synthesis:
Pyridine functions as a reagent in organic synthesis, facilitating a range of chemical reactions and contributing to the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 280-75-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,8 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 280-75:
(5*2)+(4*8)+(3*0)+(2*7)+(1*5)=61
61 % 10 = 1
So 280-75-1 is a valid CAS Registry Number.
280-75-1Relevant academic research and scientific papers
Solid-phase development of chiral phosphoramidite ligands for enantioselective conjugate addition reactions
Huttenloch, Oliver,Laxman, Eltepu,Waldmann, Herbert
, p. 4767 - 4780 (2007/10/03)
The development of a method for the optimization of chiral ligands for the steric steering of enantioselective Cu-catalyzed conjugate additions of Zn-alkyls to enones is described. The method is based on combinatorial principles and solid-phase techniques. It includes the combinatorial synthesis of chiral bispidine-derived ligands embodying a phosphoramidite group on the solid phase and their investigation in immobilized form in the conjugate addition of ZnEt2 to cyclohexenone as test reaction. The best identified ligands were also synthesized separately and investigated in its soluble form. The results obtained for the polymer-bound ligands correctly mirrored the performance of the soluble ligands. The library embodied members giving ee values varying between 3 and 67%. The "positional scanning" approach proved to be invalid for the study of the ligand system, indicating that this approach in general should be applied with care. Taken together, the method allowed for rapid and efficient optimization of the ligands and led to the development of the first enantioselective, Cu-catalyzed conjugate addition reaction with a polymer-bound ligand.
Combinatorial development of chiral phosphoramidite-ligands for enantioselective conjugate addition reactions.
Huttenloch, Oliver,Laxman, Eltepu,Waldmann, Herbert
, p. 673 - 675 (2007/10/03)
Chiral phosphoramidite ligands embodying bispidine frame work and a binaphthyl phosphoramidite for Cu-catalysed enantioselective conjugate addition reactions were developed employing principles of combinatorial and solid phase chemistry.
