280137-25-9Relevant articles and documents
5-Arylideneimidazolones with amine at position 3 as potential antibiotic adjuvants against multidrug resistant bacteria
Kaczor, Aneta,Witek, Karolina,Podlewska, Sabina,Czekajewska, Joanna,Lubelska, Annamaria,Zes?awska, Ewa,Nitek, Wojciech,Latacz, Gniewomir,Alibert, Sandrine,Pagès, Jean-Marie,Karczewska, Elzbieta,Kie?-Kononowicz, Katarzyna,Handzlik, Jadwiga
, (2019/01/30)
Searching for new chemosensitizers of bacterial multidrug resistance (MDR), chemical modifications of (Z)-5-(4-chlorobenzylidene)-2-(4-methylpiperazin-1-yl)-3H-imidazol-4(5H)-one (6) were performed. New compounds (7–17), with fused aromatic rings at posit
Bicyclic imidazole-4-one derivatives: A new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55
Rempel,Atzler,Behrenswerth,Karcz,Schoeder,Hinz,Kaleta,Thimm,Kiec-Kononowicz,Müller
, p. 632 - 649 (2014/05/06)
GPR18 and GPR55 are orphan G protein-coupled receptors (GPCRs) that interact with certain cannabinoid (CB) receptor ligands. In the present study bicyclic imidazole-4-one derivatives were discovered as new scaffolds for the development of antagonists for
The synthesis of 2-alkylthio-3-alkyl-5-arylmethylidene-4H-imidazol-4-ones
Sun, Yong,Gao, Li-Ping,Guo, Zhi-Qiang,Ding, Ming-Wu
, p. 2109 - 2116 (2007/10/03)
2-alkylthio-3-alkyl-5-arylmethylidene-4H-imidazol-4-ones were synthesized by the S-alkylation and N-alkylation of 2-thioxo-5-arylmethylidene-4- imidazolidinones, which were obtained via a tandem aza-Wittig reaction of vinyliminophosphoranes, carbon disulf
