28024-69-3 Usage
Uses
Used in Medicinal Chemistry:
DL-Cyclobutylglycine is used as a key intermediate in the synthesis of biologically active compounds for medicinal chemistry applications. Its unique cyclobutane ring and glycine residue contribute to the development of novel drug candidates with specific therapeutic properties.
Used in Pharmaceutical Development:
DL-Cyclobutylglycine is used as a building block in the creation of new pharmaceuticals. Its incorporation into drug molecules can enhance their efficacy, selectivity, and pharmacokinetic properties, leading to improved therapeutic outcomes.
Used in Materials Science:
DL-Cyclobutylglycine is used as a structural component in the development of new materials with specific properties. Its cyclobutane ring and glycine residue can be utilized to create materials with tailored characteristics for various applications in materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 28024-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,2 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 28024-69:
(7*2)+(6*8)+(5*0)+(4*2)+(3*4)+(2*6)+(1*9)=103
103 % 10 = 3
So 28024-69-3 is a valid CAS Registry Number.
28024-69-3Relevant academic research and scientific papers
A 3-cyclobutyl morphline chemical synthesis method
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, (2017/02/23)
The invention relates to a chemical synthesis method of 3-cyclobutylmorpholine. The method comprises the following steps: adding cyclobutyl formaldehyde, ammonium sulfate, aqua ammonia and cyanide into a methanol or ethanol solvent, and reacting at controlled temperature to obtain aminocyclobutyl acetonitrile; adding the aminocyclobutyl acetonitrile into hydrochloric acid, and hydrolyzing to obtain aminocyclobutyl acetic acid; adding the aminocyclobutyl acetic acid into hydrochloric acid ethanol, and reacting to prepare ethyl aminocyclobutyl acetate; dissolving the ethyl aminocyclobutyl acetate and triethylamine in a tetrahydrofuran solvent, adding chloracetyl chloride, and reacting at controlled temperature to obtain ethyl 2-cyclobutyl-2-chloropropionamidoacetate; obtaining N-(1-cyclobutyl-2-hydroxymethylethyl)chloropropanamide; obtaining 5-cyclobutylmorpholinyl-3-one; and obtaining the 3-cyclobutylmorpholine. The cyclobutyl formaldehyde used as the raw material is subjected to seven reactions to prepare the 3-cyclobutylmorpholine. The invention provides a high-efficiency synthesis method for synthesizing the compound.
