28027-16-9 Usage
Uses
Used in Pharmaceutical Industry:
4-HYDROXY-6-METHOXYQUINOLINE-3-CARBOXYLIC ACID is used as a pharmaceutical intermediate for the synthesis of various drugs, including antimalarial and antibacterial agents. Its unique structure allows for the development of new therapeutic agents with potential applications in treating a range of diseases.
Used in Research and Development:
In the field of research and development, 4-HYDROXY-6-METHOXYQUINOLINE-3-CARBOXYLIC ACID is utilized as a building block for the creation of new chemical compounds with biological activity. Its structural features enable the design and synthesis of innovative molecules with potential applications in medicine, agriculture, and other industries.
Check Digit Verification of cas no
The CAS Registry Mumber 28027-16-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,2 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 28027-16:
(7*2)+(6*8)+(5*0)+(4*2)+(3*7)+(2*1)+(1*6)=99
99 % 10 = 9
So 28027-16-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO4/c1-16-6-2-3-9-7(4-6)10(13)8(5-12-9)11(14)15/h2-5H,1H3,(H,12,13)(H,14,15)
28027-16-9Relevant academic research and scientific papers
Synthesis of novel 3,4,6-trisubstituted quinolines enabled by a Gould-Jacobs cyclization
Trah, Stephan,Lamberth, Clemens
, p. 794 - 796 (2017/03/31)
A Gould-Jacobs cyclization enabled the synthesis of several novel, so far undescribed 3,4,6-trisubstituted quinoline derivatives. They all bear substituents which are well-suited for further transformations, e.g. carboxylic acid or ester functions, haloge
Preparation of quinoline hexose analogs as novel chloroquine-resistant malaria treatments (1). Synthesis of 4-hydroxyquinoline-β-glucosides
Suzuki, Hiroshi,Aly, Nagwa S. M.,Wataya, Yusuke,Kim, Hye-Sook,Tamai, Ikumi,Kita, Masaki,Uemura, Daisuke
, p. 821 - 824 (2008/02/13)
Quinoline hexose analogs are expected to be useful as novel agents for treatment of chloroquine-resistant malaria. Here, we report preparation of 4-hydroxy quinoline-β-glucosides from anilines in 4 steps.
