280563-83-9Relevant academic research and scientific papers
Biaryl piperidines as potent and selective delta opioid receptor ligands
Liras, Spiros,McHardy, Stanton F.,Allen, Martin P.,Segelstein, Barb E.,Heck, Steven D.,Bryce, Dianne K.,Schmidt, Anne W.,Vanase-Frawley, Michelle,Callegari, Ernesto,McLean, Stafford
scheme or table, p. 503 - 507 (2010/04/05)
The design and synthesis of novel opiates are reported. Based on the message-address principle a novel class of 4,4- and 3,3-biaryl piperidines was designed and synthesized. Biological evaluation confirmed that these compounds exhibit high affinity and se
3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives
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, (2008/06/13)
The present invention relates to compounds of the formula I, wherein Z1, Z2, X, Q, R1, R2and R3are defined as in the specification, pharmaceutical compositions containing such compounds the use of suc
