28059-45-2

Upstream product

• 28059-39-4 2-benzyl-1-phenyl-3-phenylcarbamimidoyl-isothiourea; hydrochloride 
• 106-40-1 4-bromo-aniline 
• 28059-39-4 1-Phenylamidino-3-phenyl-2-S-benzylisothiocarbamide hydrochloride 

Downstream Products

• 60592-85-0 N-[3-(4-bromo-anilino)-[1,2,4]thiadiazol-5-yl]-N,N'-bis-(4-bromo-phenyl)-guanidine 

Relevant academic research and scientific papers

Dithioallophanic Acids : Interaction of Carbon Oxysulphide with S-Benzyl-N-phenyl/methylisothiocarbamide in Presence of Alkyl Halides

Interaction of carbon oxysulphide with S-benzyl-N-phenyl/methylisothiocarbamide in acetone/benzene in the presence of benzyl chloride affords benzyl thiocyanate, dibenzyl dithiocarbonate, S-benzyl-N-phenyl/methylthiocarbamate and S-benzyl-1-phenyl/methylamidino-3-phenyl/methylisothiocarbamide hydrochloride.The intermediate alkyl ester of the corresponding N-γ-substituted-β-S-benzyldithioallophanic acid could not be isolated.The mechanism for the formation of these products from the intermediate dithioallophanic acid has been rationalised.

TRITHIOALLOPHANIC ACIDS. INTERACTION OF CARBON DISULPHIDE WITH 1- PHENYL-S- BENZYLISOTHIOCARBAMIDE

Interaction of carbon disulfide and 1-phenyl- S- benzylisothicarbamide leads to several products which have been shown to arise through the decomposition of the initially formed but very unstable U-phenyl- !- S- benzyltrithioallophanic acid. The reaction, if carried out in presence of benzyl chloride, affords products that can be attributed to the formation and subsequent decomposition of the expected benzyl ester of the above trithioallophanic acid, neither of which, however, has been isolated.